Comparison of clinical characteristics and prognosis of azithromycin in the treatment of bronchial pneu-monia and lobar pneumonia in children with MP infection
Objective To explore the differences in clinical characteristics and prognosis between bron-chopneumonia and lobar pneumonia in children infected with Mycoplasma pneumoniae(MP).Methods A retro-spective analysis was conducted on 94 children with MP infection admitted to First People's Hospital of Nanyang from October 2019 to October 2021.According to the different types of diseases,the above-mentioned children were divided into bron-chopneumonia group(n=63)and lobar pneumonia group(n=31).All children were treated with azithromycin-based drug therapy.The general clinical symptoms,white blood cell count(WBC),neutrophil per-centage(NEU％),platelet count(PLT),hypersensitive C-reactive protein(CRP),immunoglobulins(IgA,IgG,IgM),interleukin-2(IL-2),interleukin-8(IL-8),and tumor necrosis factor-α(TNF-α)were compared between the two groups.?In addition,the average hospitalization time,average fever time,and incidence of complications were also compared between the two groups.Results The proportion of cases with fever symptoms exceeding 7 days in the lobar pneumonia group was higher than that in the bronchopneumonia group(P＜0.05),and the proportion of cases with wheezing symptoms was lower than that in the bronchopneumonia group(P＜0.05).There was no statisti-cally significant dif-ference in WBC,NEU％,PLT,CRP,and IgA levels between the two groups(P＞0.05).The lev-els of IgG,IgM,IL-8,and TNF-α were higher in the lobar pneumonia group than in the bronchopneumonia group(P＜0.05),while the level of IL-2 was lower in the lobar pneumonia group than in the bronchopneumonia group(P＜0.05).The average hospitalization time and fever time in the lobar pneumonia group were higher than those in the bronchopneumonia group(P＜0.05).There was no significant difference in the incidence of complications be-tween the both groups(P＞0.05).Conclusion There are significant differences in fever,wheezing symptoms,and some immunological and inflammatory factors between children with bronchopneumonia and lobar pneumonia caused by MP infection.Children with lobar pneumonia have longer fever duration and average hospitalization time,and both groups have good overall prognosis.
万方数据
维普
