Effects of awake brain static injection combined with Western medicine comprehensive treatment on in-flammatory factors and Barthel index in patients with hypertensive intracerebral hemorrhage
Objective To investigate the effect of awake brain static injection combined with Western medicine comprehensive treatment on inflammatory factors and Barthel index in patients with hypertensive intrac-erebral hemorrhage.Methods A total of 83 patients with hypertensive intracerebral hemorrhage who visited Xinzheng Tianyou Traditional Chinese Medicine Hospital from January 2018 to January 2022 were included in this study.According to the treatment plan,they were divided into a control group(41 cases)and an observation group(42 cases).After admission,symptomatic treatments such as reducing intracranial pressure were adminis-tered to both groups;The control group was treated with Olaxitam combined with 0.9％sodium chloride solution via intravenous drip,while the observation group was treated with awake brain static injection combined with 5％glucose solution via intravenous drip on the basis of the above.Continuous treatment for 14 days.The clinical ef-ficacy,hematoma situation,edema volume,serum inflammatory factor levels,neurological deficits,and daily living ability of the two groups were compared before and after treatment.Results The treatment effect in the observa-tion group was significantly better than that in the control group,the total effective rates of the two groups were 86％(36/42)and 66％(27/41)(P＜0.05).Compared to before treatment,the volumes of hematoma and edema in both groups decreased after treatment,and the reduction in the observation group was greater than that in the control group(P＜0.05).After treatment,the levels of serum IL-8,IL-1β,TNF-α,and NF-κBp65 decreased in both groups,with a greater decrease in the observation group compared to the control group(P＜0.05).After treatment,both CNDS and NIHSS scores decreased in both groups,with a greater decrease in the observation group compared to the control group.Additionally,the Barthel index increased in both groups compared to before treatment,with a larger increase in the observation group than in the control group(P＜0.05).Conclusion The combined treatment of awake brain static injection with Western medicine for hypertensive cerebral hemorrhage is effective,which can effectively enhance the clinical efficacy of patients,improve hematoma conditions,reduce edema volume,regulate serum inflammatory factor levels,and reduce the level of NF-KBp65 improves neurological deficits,enhances daily living abilities,and is beneficial for patient prognosis.
Intracranial hemorrhage,hypertensiveXin Nao Jing Zhu She YeInflammatory factorsNeurologic manifestations
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维普
