Curative effect of Qingre Lishi Zhixue Decoction and its influences on levels of urine BLD and RBC in patients with glomerular-derived hematuria of damp-heat accumulation type
Objective To explore the curative effect of Qingre Lishi Zhixue Decoction and its influences on levels of urine latent blood(BLD)and red blood cells(RBC)in patients with glomerular-derived hematuria of damp-heat accumulation type.Methods A total of 160 patients with glomerular-derived hematuria confirmed in Lishui People's Hospital were enrolled between September 2021 and September 2023.According to treatment method,they were divided into a treatment group(n=80)and a control group(n=80).The control group was treated with routine therapeutic regimen,while the treatment group was additionally treated with Qingre Lishi Zhixue Decoction.All were treated for 3 months.The scores of TCM syndromes,curative effect and occurrence of adverse reactions,BLD,RBC,24 h urinary protein quantification and centrifugal RBC before and after treatment were compared between the two groups.Results After treatment,scores of TCM syndromes(urethral burning pain,soreness of waist and abdominal distension,sole centre burning)in both groups were decreased,which were lower in treatment group than control group[(0.84±0.13)points,(0.74±0.19)points,(1.05±0.26)points vs(1.15±0.18)points,(1.38±0.22)points,(1.34±0.31)points;P＜0.05];Response rate of treatment group was higher than that of control group(93％vs 81％,P＜0.05);RBC,number of centrifugal RBC and 24 h urinary protein quantification were reduced in both groups,which were lower in treatment group than control group[(195±42)/μl,(13±3)/HP,(0.58±0.24)g/24 h vs(220±52)/μl,(16±4)/HP,(0.73±0.31)g/24 h;P＜0.05];Number of cases with BLD(++++),(+++)and(++)in treatment group was less than that in control group,while number of cases with BLD(+)and(-)was more than that in control group(P＜0.05);There was no significant difference in the occurrence of adverse reactions between the two groups(4％vs 11％,P＞0.05).Conclusion Qingre Lishi Zhixue Decoction can improve hematuria symptoms,reduce levels of urine BLD and RBC in glomerular-derived hematuria of damp-heat accumulation type,with good clinical curative effect.
Clear heat and dissolving damnpnessErythrocytes,Qing Re Li shi Zhi Xue TangDamp-heat accumulation typeGlomerular-derived hematuriaUrine latent blood
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维普
