Clinical study on the combination of traditional Chinese medicine constipation patch along the meridian and polyethylene glycol 4000 powder in the treatment of post stroke patients with heat accumulation constipation syndrome
Objective To analyze the effect of polyethylene glycol 4000 powder combined with traditional Chinese medicine constipation patch along the meridian in the treatment of heat accumulation constipation syndrome in the recovery period after stroke.Methods A total of 180 patients with post-stroke recovery constipation admitted to Tongxiang First People's Hospital from January 2021 to January 2023 were randomly divided into Group A(60 cases),Group B(60 cases),and Group C(60 cases)by a random number table method.All three groups received routine treatment.On this basis,Group A was treated with polyethylene glycol 4000 powder,Group B was treated with traditional Chinese medicine constipation patch along the meridian,and Group C was treated with traditional Chinese medicine constipation patch along the meridian combined with polyethylene glycol 4000 powder.The clinical efficacy,traditional Chinese medicine syndrome score,gastrointestinal hormones,degree of constipation,quality of life,and adverse reactions among the three groups were compared.Results Compared with the total effective rate of Group A(82%)and Group B(85%),the total effective rate of Group C(97%)was higher(χ2=6.987,4.904,P<0.05);Compared with Group A and Group B after treatment,Group C showed a more significant decrease in traditional Chinese medicine syndrome scores(t=2.686,2.127,4.155,3.331,11.487,9.555,5.635,4.829,P<0.05);Compared with group A and group B after treatment,the levels of motilin(MTL)and gastrin(GAS)in group C increased more significantly,while the levels of somatostatin(SS)and vasoactive intestinal peptide(VIP)decreased more significantly(t=6.970,8.334,12.293,25.646,8.465,7.677,4.815,3.811,P<0.05);After 1 week,2 weeks,and 4 weeks of treatment,the Wexner score of fecal incontinence in Group C was lower than that in Group A and Group B(F=15.548,13.860,20.240,P<0.05);Compared with group A and group B after treatment,the PAC-QOL score of constipation patients in group C decreased more significantly(t=7.564,5.450,5.838,6.493,6.739,13.533,8.118,8.802,P<0.05);There was no statistically significant difference in the incidence of adverse reactions among the three groups(13%,8%,10%)(χ2=0.685,P>0.05).Conclusion The combination of polyethylene glycol 4000 powder and traditional Chinese medicine constipation patch along the meridian can alleviate constipation symptoms,improve the gastrointestinal hormone secretion,promote the improvement of patient's quality of life,and do not increase adverse reactions in patients with heat accumulation constipation syndrome in the recovery period after stroke.
Traditional Chinese medicine constipation patchApply along the meridianStroke,con-valescencePolyethylene glycol 4000 powderConstipationQuality of Life
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