首页|基于属性层次模型联合逼近理想解排序法的依降钙素注射液临床合理用药评价标准的建立与应用

基于属性层次模型联合逼近理想解排序法的依降钙素注射液临床合理用药评价标准的建立与应用

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目的 建立依降钙素注射液药物利用评价细则,探讨属性层次模型(AHM)联合逼近理想解排序(TOPSIS)法在依降钙素注射液药物利用合理性评价中的应用。方法 制定依降钙素注射液药物利用评价标准,采用AHM确定各指标权重,利用TOPSIS法对杭州市萧山区中医院 156 例使用依降钙素注射液患者的用药合理性进行评价,根据评价结果制定相应的干预措施,实施措施并对干预后使用情况进行评价。结果 干预前 156 份病历中,根据评价标准用药基本合理为 73 份(46。8%),不合理的 83 份(53。2%)。疾病诊断、给药剂量、给药频率、特殊人群、症状及体征、辅助检查和实验室检查、病程记录等是导致依降钙素注射液用药不合理的主要因素。干预后 108 份病历中基本合理为 96 份(88。9%),不合理的 12 份(11。1%),与干预前用药合理情况明显改善。结论 通过AHM-TOPSIS建立了依降钙素注射液临床应用合理性评价方法,所建立的方法切实可行,依降钙素注射液在本院的不合理使用较为普遍,应引起重视。
Establishment and application of evaluation criteria for clinical rational use of Elcatonin injection based on AHM-TOPSIS method
Objective To establish the detailed rules for evaluating drug utilization of Elcatonin injection and to explore the application of Attribute Hierarchical Model(AHM)and TOPSIS method in rationally evaluating the drug utilization of Elcatonin injection.Methods Establishing the review standard of the drug utilization of El-catonin injection.The weight of each index was determined by AHM.TOPSIS method was used to evaluate the ra-tionality of the medication in 156 patients who had been treated with Elcatonin injection in Xiaoshan District Hos-pital of Traditional Chinese medicine(hereinafter referred to as"Our hospital").According to the evaluation re-sults,the corresponding intervention measures were formulated and implemented.Then the application after inter-vention was evaluated.Results Among the 156 cases before intervention,73 cases(46.8%)were basically rea-sonable and 83 cases(53.2%)were unreasonable according to the evaluation criteria.The main problems of Elca-tonin injection use were disease diagnosis,dosage,frequency of administration,special population,symptoms and signs,auxiliary examination,and laboratory examination,etc.Among the 108 medical records after intervention,96 were basically reasonable(88.9%),while 12 were unreasonable(11.1%),indicating a significant improvement in medication rationality compared to the medication before intervention.Conclusion The method established by AHM-TOPSIS to evaluate the clinical rationality of the application of Elcatonin injection is feasible.The unrea-sonable application of Elcatonin injection in our hospital is more common,which should be paid great attention to.

Elcatonin injectionAnalytic hierachical modelTOPSIS methodDrug utilization

潘丹、余亚萍、浦秋梅、汤样华、钟琳

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杭州市萧山区中医院 浙江中医药大学附属江南医院药学部,浙江杭州 311201

杭州市萧山区中医院浙江中医药大学附属江南医院骨科,浙江杭州 311201

依降钙素注射液 属性层次模型 逼近理想解排序法 药物利用

浙江省医药卫生科技计划面上项目

2019KY548

2024

中国药物与临床
中国医院协会

中国药物与临床

影响因子:0.846
ISSN:1671-2560
年,卷(期):2024.24(9)