首页|补肾通腑方治疗脊髓损伤后神经源性膀胱患者临床疗效

补肾通腑方治疗脊髓损伤后神经源性膀胱患者临床疗效

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目的 探讨补肾通腑方对脊髓损伤后神经源性膀胱(NB)患者临床疗效。方法 选择浙江省丽水市人民医院2021年8月至2023年8月脊髓损伤后NB患者94例,按治疗方法分为治疗组(47例)与对照组(47例)。对照组采用膀胱功能训练与间歇性无菌导尿治疗,治疗组在对照组基础上结合补肾通腑方治疗。2组治疗疗程4周。比较2组治疗疗效、治疗前后中医证候积分、膀胱容量和残余尿量、日平均单次尿量和日平均排尿次数及生活质量变化。结果 治疗组总有效率高于对照组(P<0。05)。2组治疗后气短自汗、面色胱白、倦怠无力和小便频多积分低于治疗前(P<0。05);治疗组治疗后气短自汗、面色晄白、倦怠无力和小便频多积分低于对照组(P<0。05)。2组治疗后膀胱容量高于治疗前,而残余尿量低于治疗前(P<0。05);治疗组治疗后膀胱容量高于对照组,而残余尿量低于对照组(P<0。05)。2组治疗后日平均单次尿量高于治疗前,而日平均排尿次数低于治疗前(P<0。05);治疗组治疗后日平均单次尿量高于对照组,而日平均排尿次数低于对照组(P<0。05)。2组治疗后泌尿症状困扰评分(USDS)低于治疗前(P<0。05);治疗组治疗后USDS评分低于对照组(P<0。05)。结论 补肾通腑方对脊髓损伤后NB患者疗效显著,且可改善患者尿动力学,提高患者生活质量。
Clinical efficacy study of Bushen Tongfu Fang on patients with neurogenic bladder after spinal cord injury
Objective To explore the clinical efficacy of Bushen Tongfu Fang in patients with neurogenic bladder(NB)after spinal cord injury(SCI).Methods A total of 94 patients with NB after SCI in Lishui People's Hospital from August 2021 to August 2023 were selected as the study subjects.They were divided into a treatment group and control group,with each 47 cases in each group.The control group was treated with bladder function training and intermittent sterile catheterization,while the treatment group received Bushen Tongfu Fang on the ba-sis of the treatment in the control group.The treatment course for two groups was 4 weeks.Compare the therapeu-tic effects of the two groups;changes in Traditional Chinese Medicine Syndrome Score,bladder capacity,residual urine volume,daily average single urine volume,daily average urination frequency,and life quality before and af-ter the treatment.Results The total effective rate in the treatment group was higher than that in the control group(P<0.05).After treatment,shortness of breath,spontaneous sweating,pale complexion,fatigue and weakness,and frequent urination were improved in both groups in comparison with those before the treatment(P<0.05);Patients in the treatment group has lower scores of shortness of breath,spontaneous sweating,pale complexion,fatigue and weakness,and frequent urination in comparison with those in the control group(P<0.05).After treatment,bladder volume was larger in both groups than that before the treatment,and the residual urine volume was less(P<0.05).In the treatment group,the bladder volume was larger than that in the higher control group,and the residual urine volume was less(P<0.05).After treatment,the average daily urine output was larger than that before the treatment,and the average daily urination frequency was lower(P<0.05).The average daily urine output in the treatment group was larger than that in the control group,and the average daily urination frequency was lower(P<0.05).After treatment,the Urinary Symptom Distress Score(USDS)scores in the two groups was than that before treat-ment(P<0.05),and the USDS score in the treatment group was lower than that in the control group(P<0.05).Conclusion The Bushen Tongfu Fang has a significant therapeutic effect on NB patients after SCI,which can improve their urodynamics and life quality.

Bu Shen Tong Fu FangSpinal cord injuriesUrinary bladder,neurogenicTreatment out-come

黄平香、毛平安、方彩莲

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丽水市人民医院康复医学科,浙江丽水 323000

补肾通腑方 脊髓损伤 膀胱,神经原性 治疗结果

2024

中国药物与临床
中国医院协会

中国药物与临床

影响因子:0.846
ISSN:1671-2560
年,卷(期):2024.24(12)