首页|补血益母丸联合屈螺酮炔雌醇片对宫腔粘连患者盆腔血流动力学的效果观察

补血益母丸联合屈螺酮炔雌醇片对宫腔粘连患者盆腔血流动力学的效果观察

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目的 分析宫腔粘连采用补血益母丸联合屈螺酮炔雌醇片治疗对患者盆腔血流动力学的影响及治疗粘连的效果。方法 选取96例2022年10月至2023年10月南阳医学高等专科学校第一附属医院妇二科宫腔粘连患者开展前瞻性研究,将96例患者按随机数字表法分组,分为对照组(48例)与试验组(48例)。对照组治疗采用屈螺酮炔雌醇片,试验组治疗采用补血益母丸联合屈螺酮炔雌醇片,2组均服药3个月。对2组患者临床效果,治疗前及治疗2、3个月后子宫容积与子宫内膜厚度,治疗前后人绒毛膜促性腺激素(HCG)、雌二醇(E2)水平及血管血流指数、阻力指数、血流峰值速度进行比较。结果 经过临床治疗对照组、试验组的临床有效分别为40、47例,占 83%、98%,试验组较对照组高;2组治疗2、3个月后相较于治疗前,子宫容积增加,试验组较对照组增加明显,子宫内膜厚度增厚,试验组较对照组高;2组治疗后相较于治疗前,HCG水平及阻力指数降低,试验组较对照组低,E2水平及血管血流指数、血流峰值速度升高,试验组较对照组高(P<0。05)。结论 补血益母丸联合屈螺酮炔雌醇片治疗宫腔粘连临床疗效较好,可有效恢复子宫宫腔状态,提高雌激素水平、改善盆腔血流动力学。
Effects of Buxue Yimu Pills combined with drospirenone ethinylestradiol tablets on pelvic blood flow in patients with intrauterine adhesion
Objective To analyze the effects of Buxue Yimu Pills combined with drospirenone ethinylestradiol tablets on pelvic blood flow in treating intrauterine adhesions.Methods A prospective study was carried out in 96 patients with intrauterine adhesion in First Affiliated Hospital of Nanyang Medical College from October 2022 to October 2023.The patients were divided into a control group(48 cases)and an experimental group(48 cases)by the method of random number table.The control group was treated with drospirenone ethinylestradiol tablets,and the experimental group was treated with Buxue Yimu pills combined with drospirenone ethinylestradiol tablets.Both groups were treated for 3 months.Compared the clinical efficacy in both groups:uter-ine volume and endometrial thickness before treatment and 2 to 3 month after treatment,levels of human chorionic gonadotropin(HCG)and estradiol(E2)before and after treatment,vascular blood flow index,resistance index,peak blood flow velocity.Results After clinical treatment,the clinically effective patients in the control group and the experimental group were 40 cases and 47 cases,accounting for 83%and 98%,respectively.After 2 to 3 months of treatment,the uterine volume and the endometrial thickness in both groups increased in comparison with that be-fore the treatment,and the variations in the experimental group was larger than those in the control group.Com-pared with that before treatment,the HCG and the resistance index were decreased in both groups,while E2,vas-cular blood flow index and peak blood flow velocity were increased in the experimental group.The variations in the experimental group was larger than those in the control group(P>0.05).Conclusion Buxue Yimu pills com-bined with drospirenone ethinylestradiol tablets has good clinical effect in the treatment of intrauterine adhesion,which can effectively restore uterine,improve sex hormone,and ameliorate pelvic blood flow.

Intrauterine adhesionBu Xue Yi Mu WanHemodynamicsPelvic blood flowDrospiroone ethinylestradiol tablets

冯华南、陈亚敏

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南阳医学高等专科学校第一附属医院妇二科,河南南阳 473000

阴道闭锁 补血益母丸 血流动力学 屈螺酮炔雌醇片

2024

中国药物与临床
中国医院协会

中国药物与临床

影响因子:0.846
ISSN:1671-2560
年,卷(期):2024.24(12)