Curative effect of self-made Qingre Runmu Decoction combined with Zhu's Fengchi Three Acupuncture and periocular acupuncture in the elderly with xerophthalmia caused by meibomian gland dysfunction
Objective To investigate the therapeutic effect of the combination of self-developed Qingre Runmu Decoction,Zhu's Fengchi three acupuncture,and acupuncture points around the eyes on dry eye caused by meibomian gland dysfunction in the elderly.Methods From August 2021 to August 2023,a total of 109 el-derly patients with xerophthalmia caused by meibomian gland dysfunction were enrolled in ophthalmology depart-ment of the hospital.According to different treatment methods,the patients were divided into group A(53 cases,routine western medicine)and group B(56 cases,self-made Qingre Runmu Decoction combined with Zhu's Fengchi three acupuncture and periocular acupuncture on basis of group A).All patients were treated for 3 months.The treatment effectiveness,xerophthalmia degree[Ocular Surface Disease Index(OSDI)based on interna-tional standards],meibomian gland function(eyelid discharge capacity,eyelid secretion characters),corneal stain-ing,non-invasive break-up time and incidence of complications(corneal ulcer,corneal perforation,secondary bac-terial infection)were compared between the two groups.Results The treatment efficacy of group B was higher than that of group A(95％vs 81％,P＜0.05).The xerophthalmia degree in group B[normal(63％),mild(32％),moderate(5％),severe(0)]was milder than that in group A[normal(41％),mild(47％),moderate(8％),severe(4％);P＜0.05].The normal rate of eyelid discharge capacity(73％)and eyelid secretion characters(68％)in group B were higher than those in group A(51％,47％;P＜0.05).The score of corneal staining in group B was lower than that of group A[(4.6±0.7)points vs(6.5±0.8)points],and non-invasive break-up time was longer than that of group A[(11.0±1.3)s vs(10.3±1.1)s;P＜0.05].There was no significant difference in incidence of complications between group B and group A(13％vs 8％,P＞0.05).Conclusion The self-developed Qingre Runmu Decoction combined with Zhu's Fengchi Three Acupuncture and periocular acupuncture has a significant effect on treating dry eyes caused by meibomian gland dysfunction in the elderly.It can effectively alleviate xerophthalmia symp-toms,recover eyelid function and enhance tear film stability.
Self-made Qingre Runmu DecoctionZhu's Fengchi three acupunctureAged Meibomian gland dysfunctionXerophthalmia
万方数据
维普
