Therapeutic effect of ligustrazine injection on acute ischemic cerebral infarction
Objective To explore the therapeutic effect of ligustrazine injection on acute ischemic cerebral infarction(stroke-meridian).Methods A total of 125 patients with acute ischemic cerebral infarction(stroke meridian)were randomly divided into a control group(63 cases)and an study group(62 cases).The control group received conventional basic drug treatment,while the study group received treatment with ligustrazine injection in addition to conventional basic drug treatment.After treatment,the overall effective rate,serum inflammatory factors TNF-α,CRP,and NSE levels,as well as blood viscosity indicators PSV,HSV,and LSV levels were compared between the two groups.Results After treatment,the total effective rate of the study group(87.1％,54/62)was significantly higher than that of the control group(71.4％,45/63),and the difference was statistically significant(P＜0.05).The levels of serum inflammatory factors TNF-α,CRP,and NSE in both groups were significantly lower than those before treatment,and the differences were statistically significant(P＜0.05).Moreover,the degree of reduction in the study group was significantly higher than that in the control group,and the difference was statistically significant(P＜0.05).The levels of blood viscosity indicators PSV,HSV,and LSV in both groups were significantly lower than those before treatment,and the differences were statistically significant(P＜0.05).Furthermore,the degree of reduction in the study group was significantly higher than that in the control group,and the difference was statistically significant(P＜0.05).There was no statistically significant difference in adverse reactions between the two groups after treatment(P＞0.05).Conclusion Ligustrazine injection can improve the overall treatment efficiency of acute ischemic cerebral infarction(stroke-meridian),reduce the level of serum inflammatory factors,and reduce blood viscosity to promote blood circulation.
Chuan Xiong Qin Zhu She YeBrain infarctionBlood viscosityTreatment outcomeInflammatory factors
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维普
