Curative effect and safety of San'ao Tablet combined with Qiangli Pipa Syrup in cough after infection
Objective To explore the curative effect and safety of San'ao tablet combined with Qiangli Pipa Syrup in cough after infection.Methods A retrospective analysis was performed on the clinical data of 80 patients with cough after infection in Lishui People's Hospital between January 2022 and December 2023.Ac-cording to different treatment methods,patients were divided into a routine group(37 cases,routine treatment)and a combination group(43 cases,San'ao Tablet combined with Qiangli Pipa Syrup).All patients were treated for 14 d.The response rate of treatment,scores of TCM symptoms(cough,asthma,expectoration,lung rales),daytime and nighttime cough,immune function[immunoglobulin A(IgA),immunoglobulin G(IgG),immunoglobulin M(IgM)],inflammatory factors[tumor necrosis factor α(TNF-α),interleukin-6(IL-6),interleukin-8(IL-8)]and adverse drug reactions(dizziness,drowsiness,nausea and vomiting)were compared between the two groups.Results The re-sponse rate of treatment in combination group was higher than that in the routine group(93％vs 76％,P＜0.05).The scores of TCM symptoms(cough,asthma,expectoration,lung rales)in the combination group were lower than those in the routine group[(1.24±0.35)points,(1.17±0.29)points,(1.01±0.41)points,(1.33±0.45)points vs(1.85±0.42)points,(1.74±0.37)points,(1.76±0.37)points,(1.69±0.32)points;P＜0.05].The scores of daytime and night-time cough in the combination group were lower than those in the routine group[(0.78±0.21)points,(0.76±0.24)points vs(0.97±0.23)points,(0.91±0.22)points;P＜0.05].Levels of IgA,IgG and IgM were higher than those in the routine group[(1.63±0.24)g/L,(9.65±1.33)g/L,(1.21±0.37)g/L vs(1.27±0.21)g/L,(7.32±1.68)g/L,(0.88±0.25)g/L;P＜0.05].Levels of TNF-α,IL-6 and IL-8 were lower than those in the routine group[(12.6±1.2)pg/ml,(162±8)pg/ml,(9.5±2.8)pg/ml vs(15.4±1.2)pg/ml,(176±10)pg/ml,(11.6±2.6)pg/ml;P＜0.05].The incidence rate of adverse reactions was lower than that in the routine group(5％vs 22％,P＜0.05).Conclusion Curative effect of San'ao Tablet combined with Qiangli Pipa Syrup is significant in patients with cough after infection,which can effectively improve cough symptoms and enhance immune function.This combination therapy with high safety also reduces inflammatory response.
CoughSan'ao tabletQiang Li Pi Pa LuTreatment outcome
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