Effects of uterine artery embolization combined with methotrexate and uterine pregnancy formula on bleeding during curettage,β-HCG recovery time,and menstrual recovery time in patients with scarred pregnancy
Objective To investigate the effects of uterine artery embolization(UAE)combined with methotrexate and uterine pregnancy formula on the amount of bleeding,β-human chorionic gonadotropin(β-HCG)levels,and menstrual recovery time during cesarean section scar pregnancy(CSP)curettage.Methods A total of 66 CSP patients admitted to the First Hospital of Ninghai County from January 2018 to January 2021 were select-ed,and their baseline data were collected.The patients were divided into an observation group(29 cases,under-going UAE+curettage surgery+methotrexate+uterine pregnancy formula)and a control group(37 cases,undergo-ing UAE+curettage surgery)depending on treatment methods.The perioperative indicators,β-HCG levels,men-strual recovery time,and incidence of adverse reactions of the two groups were statistically analyzed.Results The age of 66 CSP patients was(34±4)years old,with HCG levels of(25 125±3 784)U/L and menstrual recovery time of(3.8±0.8)months.The hospitalization time,intraoperative bleeding volume,and duration of vaginal bleeding in the observation group were significantly less than those in the control group(P＜0.05).The recovery time of serum β-HCG levels and menstrual cycle in the observation group was significantly shorter than that in the control group(P＜0.05).The total incidence of adverse reactions in the observation group and the control group was 10％and 16％,respectively,with no statistically significant difference(P＞0.05).Conclusion The combination of methotrexate and uterine pregnancy formula can effectively reduce the amount of bleeding during curettage in CSP patients,shorten the time for β-HCG levels to return to normal and menstrual recovery time,and is worthy of clini-cal promotion and application.
PregnancyUterine artery embolizationDilatation and curettageChorionic gonadotropin
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