Effects of remimazolam or propofol combined with remifentanil anesthesia on hemodynamic indices,nau-sea and vomiting in children undergoing strabismus surgery
Objective To investigate the effects of remimazolam or propofol combined with remifentanil anesthesia on hemodynamic indices,nausea and vomiting in children undergoing strabismus surgery.Methods A retrospective analysis was conducted on the clinical data of a total of 82 children undergoing strabismus surgery treated in Second People's Hospital of Puyang from August 2022 to August 2023.The patients were divided into the remimazolam group(41 cases)and the propofol group(41 cases)according to different anesthesia methods.The propofol group received anesthesia with propofol combined with remifentanil,while the remimazolam group re-ceived anesthesia with remimazolam combined with remifentanil.Hemodynamics,extubation and recovery time,and adverse reactions were compared between the two groups.Results At intubation and the end of surgery,the mean arterial pressure(MAP),heart rate(HR),and blood oxygen saturation(SpO2)in both groups were lower than those at pre-initiation of anaesthesia,and the values in the remimazolam group were higher than those in the propofol group(P＜0.05).The incidence rates of postoperative nausea(PON),postoperative vomiting(POV),and in-jection pain in the remimazolam group were lower than those in the propofol group(P＜0.05).There were no statis-tically significant differences in extubation and recovery time,drowsiness,bradycardia,and hypotension incidence rates between the two groups(P＞0.05).Conclusion The application of remimazolam combined with remifentanil anesthesia in stra-bismus surgery achieved favorable outcomes,stabilizing the MAP,HR,and SpO2 of the patients,reducing the inci-dence of PON,POV,and injection pain,while not prolonging the recovery and extubation time.
StrabismusAnesthesiaRemazolamPropofolRemifentanilPostoperative nausea and vomiting
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