Clinical study on the combination of Buzhong Yiqi,Yishen Yangfei Decoction and conventional western medicine in the treatment of chronic glomerulonephritis deficiency type of lung and kidney Qi
Objective To explore the clinical effect of Buzhong Yiqi,Yishen Yangfei decoction combined with conventional western medicine in the treatment of chronic glomerulonephritis (CGN) deficiency type of lung and kidney Qi. Methods A total of 102 patients with CGN of lung kidney Qi deficiency type admitted to Wen-zhou Traditional Chinese Medicine Hospital from April 2020 to September 2021 were selected and divided into a control group and a combination group,with 51 cases in each group,according to the treatment method. The con-trol group received conventional western medicine treatment,while the combined group received conventional western medicine treatment with combined. The traditional Chinese medicine (TCM) symptom score,renal function indexes[serum cystatin C (CysC),serum creatinine (Scr),blood urea nitrogen (BUN),24-hour urinary protein quan-tification (24h-UP)]before and after treatment,clinical efficacy,immune indexes (CD3+,CD4+,CD8+,and CD4+/CD8+) before and after treatment and drug safety were compared between the two groups. Results After treat-ment,TCM symptom score,renal function index (CysC,Scr,BUN,24h-UP) and CD8+in combination group were lower than those in control group,CD3+,CD4+,CD4+/CD8+and total effective rate were higher than those in control group (P<0.05). There was no difference in the incidence of adverse reactions between the two groups (P>0.05). Conclusion For patients with CGN of lung kidney Qi Deficiency type,Buzhong Yiqi,Yishen Yangfei decoction with conventional western medicine can effectively reduce their clinical symptoms,improve renal function and en-hance immunity,and the curative effect is remarkable and the safety is high.
Tonify and replenish the middle qiYishen Yangfei DecoctionGlomerulonephritis,chronicSyndrome of Qi deficiency of lung and kidneyTreatmentout come
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