首页|睡眠丸贴剂联合常规药物治疗对急性心肌梗死患者经皮冠状动脉术后心肌损伤睡眠质量的影响

睡眠丸贴剂联合常规药物治疗对急性心肌梗死患者经皮冠状动脉术后心肌损伤睡眠质量的影响

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目的 分析穴位贴敷睡眠丸联合常规治疗对急性心肌梗死(AMI)患者经皮冠状动脉介入术(PCI)后心肌损伤、睡眠质量的影响。方法 以2021年6月至2023年3月浙江省杭州市临平区第一人民医院收治的150例行PCI的AMI患者为研究对象。采用随机数字表法将其分为对照组(75例,常规治疗)和观察组(75例,常规治疗+睡眠丸穴位贴敷治疗)。对比2组的心肌损伤指标、心脏超声指标水平以及睡眠质量、生活质量水平。结果 治疗2周后,观察组肌钙蛋白Ⅰ(cTnⅠ)、N末端钠尿肽前体(NT-proBNP)较对照组低(t=3。265、4。265、5。035,P<0。05);术后3个月,观察组左心室射血分数(LVEF)水平较对照组高(t=4。235、5。038、5。892,P<0。05),左心室舒张末期内径(LVEDD)、左心室收缩末期内径(LVESD)较对照组比较差异无统计学意义(t=0。665、0。765、0。780,P>0。05),观察组匹斯堡睡眠质量指数(PSQI)评分及心肌梗死多维度评估量表(MIDAS)评分低于对照组(t=4。685、5。368、5。032,P<0。05)。结论 穴位贴敷睡眠丸联合常规治疗对AMI患者PCI后心肌损伤具有改善作用,且可提高心功能、睡眠质量,进而提高患者生活质量。
Effects of sleep pill patch combined with conventional medication treatment on myocardial injury and sleep quality in patients with acute myocardial infarction after PCI
Objective To explore the effect of acupoint application (sleep pills) combined with routine treatment on myocardial injury and sleep quality after percutaneous coronary intervention (PCI) in patients with acute myocardial infarction (AMI). Methods A total of 150 AMI patients who underwent PCI at the First People's Hospital of Linping District,Hangzhou City,Zhejiang Province,from June 2021 to March 2023,were enrolled in this study. They were randomly divided into a control group (n=75,receiving conventional treatment) and an ob-servation group (n=75,receiving conventional treatment plus acupoint application therapy with sleep pill) using a random number table method. The levels of myocardial injury indicators,echocardiographic parameters,sleep quality,and quality of life were compared between the two groups. Results After 2 weeks of treatment,the levels of cTnⅠ and NT proBNP in the observation group were lower than those in the control group (t=3.265,4.265,5.035,P<0.05);three months after surgery,the left ventricular ejection fraction (LVEF) level in the observation group was higher than that in the control group (t=4.235,5.038,5.892,P<0.05),while there was no significant dif-ference in left ventricular end diastolic diameter (LVEDD) and left ventricular end systolic diameter (LVESD) be-tween the 2 group (t=0.665,0.765,0.780,P>0.05),respectively. The Pittsburgh Sleep Quality Index (PSQI) scores and MIDAS in the observation group were lower than those in the control group (t=4.685,5.368,5.032,P<0.05). Conclusion Acupoint application (sleep pills) combined with routine treatment can improve myocardial injury in AMI patients after PCI,enhance cardiac function and sleep quality,and thus improve the overall quality of life.

Acupoint skicking therapyMyocardial infarctionPercutaneous coronary interventionMyocardial injurySleep quality

朱姗姗、姚凌燕、李娜

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浙江省杭州市临平区第一人民医院二十病区心脏康复科,浙江杭州 311199

浙江省杭州市临平区第一人民医院心血管内科,浙江杭州 311199

穴位贴敷疗法 心肌梗死 经皮冠状动脉介入治疗 心肌损伤 睡眠质量

2024

中国药物与临床
中国医院协会

中国药物与临床

影响因子:0.846
ISSN:1671-2560
年,卷(期):2024.24(24)