Effects of Modified Electroconvulsive Therapy under Different Muscle Relaxants and Propofol Anesthesia on Patients with Schizophrenia
Objective:To investigate the effect of modified electroconvulsive therapy(MECT)under different muscle relaxants and Propofol anesthesia on patients with schizophrenia(SZ).Method:A total of 78 patients with SZ treated with MECT at Third People's Hospital of Ganzhou from April 2021 to September 2022 were selected,were randomly divided into control group and observation group,with 39 cases in each group.The control group was treated with Succinylcholine + Propofol anesthesia,and the observation group was treated with Vecuronium Bromide + Propofol anesthesia,both groups were treated with MECT for 3 weeks.Systolic blood pressure(SBP),diastolic blood pressure(DBP),heart rate(HR),and arterial oxygen saturation(SaO2)were compared between the two groups during the perioperative period of anesthesia;onset time of muscle relaxants,the recovery time of spontaneous respiration,the awakening time and the symptoms severity[positive and negative syndrome scale(PANSS)]were compared between the two groups.Result:During and after anesthesia,SBP,DBP,and HR in both groups were increased compared with those before anesthesia,but the observation group were showed smaller changes(P＜0.05).There was no statistically significant difference in perioperative SaO2 between the two groups(P＞0.05).Compared with the control group,onset time of muscle relaxants,the recovery time of spontaneous respiration and the awakening time in the observation group were shorter(P＜0.05).After treatment,the PANSS score of the observation group was lower than that of the control group(P＜0.05).Conclusion:Compared with Succinylcholine,MECT under Vecuronium Bromide combined with Propofol anesthesia can maintain the stability of vital signs of SZ patients,shorten the recovery time of anesthesia,and reduce the symptoms of patients.
国家科技期刊平台
NSTL
万方数据
维普
