摘要
目的:探讨超声对敌草快中毒患者心肾损伤评估的价值.方法:回顾性分析阜阳市人民医院收治的 70 例敌草快中毒患者的临床资料,根据入院 6 h内是否发生心肾损伤分为心肾损伤组(n=15)与非心肾损伤组(n=55).患者行超声检查测定肝固有动脉血流峰值流速(Vmax)、阻力指数(RI),对比两组患者降钙素原、肌酸激酶(CK)、血尿素氮(BUN)、血肌酐(Scr)水平及Vmax、RI,用Pearson法分析CK、BUN、Scr及Vmax、RI与心肾损伤的相关性.绘制受试者操作特征(ROC)曲线,分析超声对敌草快中毒患者入院 6 h内发生心肾损伤的评估价值.结果:两组降钙素原比较,差异无统计学意义(P＞0.05),心肾损伤组CK、BUN、Scr、Vmax、RI均高于非心肾损伤组(P＜0.05).Pearson结果显示,CK、BUN、Scr、Vmax、RI与心肾损伤均呈正相关(P＜0.05).ROC曲线结果显示,CK、BUN、Scr、Vmax、RI单独评估敌草快中毒患者入院 6 h内发生心肾损伤的AUC分别为 0.791、0.802、0.821、0.737,Vmax、RI联合检测的AUC高于各指标单一检测(P＜0.05).结论:CK、BUN、Scr、Vmax、RI在评估敌草快中毒患者入院 6 h内发生心肾损伤中均具有重要价值,且Vmax联合RI评估的价值更高.
Abstract
Objective:To investigate the value of ultrasound in the evaluation of cardiorenal injury in patients with Dquat poisoning.Method:The clinical data of 70 patients with Dquat poisoning admitted to Fuyang People's Hospital were retrospectively analyzed.According to whether cardiorenal injury occurred within 6 h after admission,they were divided into cardiorenal injury group(n=15)and non-cardiorenal injury group(n=55).The peak flow velocity(Vmax)and resistance index(RI)of the proper hepatic artery were measured by ultrasonography.The levels of procalcitonin,creatine kinase(CK),blood urea nitrogen(BUN),serum creatinine(Scr),Vmax and RI were compared between the two groups.Pearson method was used to analyze the correlation between CK,BUN,Scr,Vmax,RI and cardiorenal injury.Receiver operating characteristic(ROC)curve was drawn to analyze the value of ultrasound in the evaluation of cardiorenal injury in patients with Dquat poisoning within 6 h after admission.Result:There was no significant difference in procalcitonin between the two groups(P＞0.05).CK,BUN,Scr,Vmax and RI in the cardiorenal injury group were higher than those in the non-cardiorenal injury(P＜0.05).Pearson's results showed that CK,BUN,Scr,Vmax and RI were positively correlated with cardiorenal injury(P＜0.05).ROC curve results showed that the AUC of single assessment of CK,BUN,Scr,Vmax and RI for cardiorenal injury in patients with Dquat poisoning within 6 h after admission respectively was 0.791,0.802,0.821 and 0.737,and the AUC of the combined detection of Vmax and RI was higher than that of the single detection of each index(P＜0.05).Conclusion:CK,BUN,Scr,Vmax and RI all have important value in the assessment of cardiorenal injury in patients with Dquat poisoning within 6 h after admission,and the value of Vmax combined with RI is higher.
基金项目
安徽省医学会急诊医学临床研究项目(Ky2021011)
国家科技期刊平台
NSTL
维普
万方数据