中国医学创新2024，Vol.21Issue(2) ：32-35.DOI:10.3969/j.issn.1674-4985.2024.02.007

单侧双通道内镜下腰椎间植骨融合内固定术治疗退行性腰椎滑脱的临床研究

Clinical Study of Lumbar Intervertebral Bone Graft Fusion and Internal Fixation under Unilateral Biportal Endoscopic in the Treatment of Degenerative Lumbar Spondylolisthesis

胡波 陈萍 陆文杰 李思云 李耀华 周湘桂 刘虹 陈华龙 谢非
中国医学创新2024，Vol.21Issue(2) ：32-35.DOI:10.3969/j.issn.1674-4985.2024.02.007
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单侧双通道内镜下腰椎间植骨融合内固定术治疗退行性腰椎滑脱的临床研究

Clinical Study of Lumbar Intervertebral Bone Graft Fusion and Internal Fixation under Unilateral Biportal Endoscopic in the Treatment of Degenerative Lumbar Spondylolisthesis

胡波 1陈萍 1陆文杰 1李思云 1李耀华 1周湘桂 1刘虹 2陈华龙 1谢非1
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作者信息

  • 1. 江西省中西医结合医院骨伤二科 江西 南昌 330000
  • 2. 江西省中西医结合医院康复二科 江西 南昌 330000
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摘要

目的:探究单侧双通道内镜(UBE)下腰椎间植骨融合内固定术治疗退行性腰椎滑脱(DLS)的临床价值.方法:选取 2020 年 3 月—2023 年 1 月江西省中西医结合医院收治的 60 例DLS患者,根据随机数字表法分为两组,即对照组(n=30)、观察组(n=30).对照组进行传统手术治疗,观察组接受UBE下腰椎间植骨融合内固定术治疗.比较两组手术相关指标、疼痛程度[视觉模拟评分法(VAS)]、炎症指标[白细胞计数(WBC)、中性粒细胞计数(NE)、C反应蛋白(CRP)];随访 3 个月,比较椎间融合率.结果:观察组术中出血量少于对照组,住院时间短于对照组,椎间融合率高于对照组,差异均有统计学意义(P<0.05).两组手术用时比较,差异无统计学意义(P>0.05).术后 3 d、7 d、1 个月,两组VAS评分逐渐下降,且观察组均低于对照组,差异均有统计学意义(P<0.05).术后 2 d,两组WBC、NE、CRP水平均有所升高,但观察组均低于对照组,差异均有统计学意义(P<0.05).结论:UBE下腰椎间植骨融合内固定术用于DLS患者中,可减少出血量,减轻患者术后疼痛感及炎症反应程度,提高椎间融合率.

Abstract

Objective:To investigate the clinical value of unilateral biportal endoscopic(UBE)lumbar intervertebral bone graft fusion and internal fixation in the treatment of degenerative lumbar spondylolisthesis(DLS).Method:A total of 60 DLS patients admitted to Jiangxi Hospital of Integrated Traditional and Western Medicine from March 2020 to January 2023 were selected and divided into two groups according to random number table method,control group(n=30)and observation group(n=30).The control group received traditional surgery,and the observation group received UBE lumbar intervertebral bone graft fusion and internal fixation.Operation-related indexes,pain degree[visual analogue scale(VAS)],inflammatory indexes[white blood cell count(WBC),neutrophil count(NE),C reactive protein(CRP)]were compared between the two groups,the interbody fusion rate was compared after 3 months of follow-up.Result:The intraoperative bleeding volume in the observation group was less than that in the control group,and the hospital stay was shorter than that in the control group,and the interbody fusion rate was higher than that in the control group,the differences were statistically significant(P<0.05).There was no significant difference in operation time between the two groups(P>0.05).After 3 days,7 days and 1 month,VAS scores of both groups decreased gradually,and those in the observation group were lower than those in the control group,the differences were statistically significant(P<0.05).2 days after surgery,the levels of WBC,NE and CRP in both groups were increased,but those in the observation group were lower than those in the control group,the differences were statistically significant(P<0.05).Conclusion:The use of UBE in DLS patients can reduce the bleeding volume,reduce the degree of postoperative pain and inflammation,and improve the rate of interbody fusion.

关键词

退行性腰椎滑脱/单侧双通道内镜/腰椎间植骨融合内固定术/疼痛度

Key words

Degenerative lumbar spondylolisthesis/Unilateral biportal endoscopic/Lumbar intervertebral bone graft fusion and internal fixation/Pain degree

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基金项目

江西省卫生健康委科技计划项目(202311239)

出版年

2024
中国医学创新
中国保健协会

中国医学创新

影响因子：1.706
ISSN：1674-4985
参考文献量18
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