中国医学创新2024，Vol.21Issue(2) ：79-83.DOI:10.3969/j.issn.1674-4985.2024.02.018

刘氏毫火针改善脑卒中后上肢痉挛性瘫痪的效果及机制

Effect and Mechanism of Liu's Milli-fire Needle in Improving Spastic Paralysis of Upper Limb after Stroke

谢淦全 梁智跃 付晴 廖仲波 周锐钧 张振钊 胡斌彬 周光辉
中国医学创新2024，Vol.21Issue(2) ：79-83.DOI:10.3969/j.issn.1674-4985.2024.02.018
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  • 万方数据

刘氏毫火针改善脑卒中后上肢痉挛性瘫痪的效果及机制

Effect and Mechanism of Liu's Milli-fire Needle in Improving Spastic Paralysis of Upper Limb after Stroke

谢淦全 1梁智跃 1付晴 2廖仲波 1周锐钧 1张振钊 1胡斌彬 3周光辉1
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作者信息

  • 1. 东莞市松山湖中心医院康复医学科 广东 东莞 523000
  • 2. 东莞市松山湖中心医院功能检查科 广东 东莞 523000
  • 3. 东莞市松山湖中心医院神经内科 广东 东莞 523000
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摘要

目的:探讨刘氏毫火针改善脑卒中后上肢痉挛性瘫痪的效果及相关机制.方法:选择2021年4 月—2022 年 10 月东莞市松山湖中心医院康复医学科及神经内科脑卒中后上肢痉挛性瘫痪患者 100 例,采用随机数字表法分为对照组(n=50)、观察组(n=50).对照组给予常规康复治疗,观察组在对照组基础上增加刘氏毫火针治疗.比较两组治疗第 2、4、8 周临床效果及治疗前、治疗第 2、4、8 周Fugl-Meyer上肢运动量表(FMA-UE)评分、Barthel指数(BI)评分、美国国立卫生研究院卒中量表(NIHSS)评分、血清总胆固醇/高密度脂蛋白胆固醇(TC/HDL-C)、载脂蛋白B(ApoB)水平.结果:治疗第 2、4、8周,观察组总有效率均高于对照组(P<0.05);治疗第 2、4、8 周,观察组FMA-UE评分、BI评分均高于对照组(P<0.05);治疗第 2、4、8 周,观察组NHISS评分均低于对照组(P<0.05);治疗第 2、4、8 周,两组血清TC/HDL-C、ApoB水平均低于治疗前,且观察组均较对照组改善更明显(P<0.05).结论:刘氏毫火针可缓解脑卒中后上肢痉挛性瘫痪患者上肢痉挛状态,提高运动能力及日常生活能力,并能有效修复神经缺损,其机制可能与调节血清TC/HDL-C、ApoB表达有关.

Abstract

Objective:To investigate the effect and related mechanism of Liu's milli-fire needle in improving spastic paralysis of upper limb after stroke.Method:A total of 100 patients with spastic paralysis of upper limb after stroke in the Rehabilitation Medicine Department and Neurology Department of Dongguan Songshan Lake Central Hospital from April 2021 to October 2022 were selected and divided into control group(n=50)and observation group(n=50)by random number table method.The control group was given routine rehabilitation treatment,and the observation group was added Liu's milli-fire needle treatment on the basis of the control group.The clinical efficacy of the two groups at the 2nd,4th and 8th week were compared,and the scores of Fugl-Meyer upper limb exercise scale(FMA-UE),Barthel index(BI),national institutes of health neurological deficit scale(NIHSS),serum TC/HDL-C,apolipoprotein B(ApoB)were compared before treatment and at the 2nd,4th and 8th week of treatment.Result:At the 2nd,4th and 8th week of treatment,the total effective rates of observation group were higher than those of control group(P<0.05).At the 2nd,4th and 8th week of treatment,FMA-UE scores and BI scores in observation group were higher than those in control group(P<0.05).At the 2nd,4th and 8th week of treatment,NHISS scores in observation group were lower than those in control group(P<0.05).At the 2nd,4th and 8th week of treatment,serum TC/HDL-C and ApoB levels in both groups were lower than before treatment,and the improvement in observation group were more obvious than those in control group(P<0.05).Conclusion:Liu's mile-fire needle can relieve spasticity of the upper limb in patients with spastic paralysis of the upper limb after stroke,improve movement ability and daily living ability,and effectively repair nerve defects,the mechanism may be related to the regulation of serum TC/HDL-C and ApoB expression.

关键词

刘氏毫火针/脑卒中/上肢痉挛性瘫痪/总胆固醇/高密度脂蛋白胆固醇/载脂蛋白B

Key words

Liu's milli-fire needle/Stroke/Spastic paralysis of upper limb/TC/HDL-C/ApoB

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基金项目

东莞市科技局社会发展科技面上项目(20221800900602)

东莞市卫生健康局周光辉广东省名中医传承工作室项目(粤中医办函[2020]1号)

出版年

2024
中国医学创新
中国保健协会

中国医学创新

影响因子：1.706
ISSN：1674-4985
参考文献量15
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