Prognostic Value of Serum Procalcitonin Combined with Hypersensitive C Reactive Protein in Children with Lobar Pneumonia
Objective:To investigate the prognostic value of procalcitonin(PCT)combined with hypersensitive C reactive protein(hs-CRP)in children with lobular pneumonia.Method:A total of 103 children with lobular pneumonia who were hospitalized in the Pediatric Ward of Huai'an Second People's Hospital from January 2019 to January 2022 were selected as the study objects.Serum PCT and hs-CRP levels of all children were detected,and the children were divided into poor treatment group(n=10)and cured group(n=93)according to the prognosis.Clinical data of the children were collected,and the risk factors of lobed pneumonia were analyzed by multivariate logistic regression,and receiver operating characteristic(ROC)curves were developed,area under the curve(AUC)was used to evaluate the predictive value of serum PCT and hs-CRP in lobar pneumonia.Result:There were no significant differences in age,sex,height,weight and white blood cell count between the two groups(P>0.05);the levels of hs-CRP and PCT in poor treatment group were higher than those in cured group(P<0.05).Multivariate logistic regression analysis showed that serum PCT and hs-CRP were risk factors for poor treatment of lobular pneumonia(P<0.05).The AUC of single and combined prediction of serum PCT and hs-CRP for poor treatment of lobar pneumonia were 0.805,0.810 and 0.921,respectively,and the AUC of combined prediction was higher than those of single prediction(P<0.05).Conclusion:The levels of serum PCT and hs-CRP in children with lobar pneumonia are abnormal,and the levels of blood PCT and hs-CRP are closely related to the poor treatment of lobar pneumonia,and the two are of great value in predicting the poor treatment of lobar pneumonia,and the combined prediction value is higher in predicting the poor treatment of lobar pneumonia.
ProcalcitoninHypersensitive C reactive proteinLobar pneumoniaPoor treatment
万方数据
维普
