Vascular cognitive impairment(VCI)is a kind of clinical syndrome caused by cerebrovascular disease and its risk factors,which is manifested by different degrees of cognitive dysfunction.As an independent risk factor closely related to cerebrovascular disease,hyperhomocysteinemia(HHcy)has been shown in numerous studies in recent years to be directly or indirectly related to the occurrence and development of VCI.The purpose of this paper is to review the new progress in the relationship between HHcy and VCI,to provide ideas for the prevention and treatment of VCI.
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