Application Effect of Live Combined Bifidobacterium,Lactobacillus and Enterococcus Capsules Combined with Pinaverium Bromide in Patients with Irritable Bowel Syndrome
Objective:To investigate the application effect of Live Combined Bifidobacterium,Lactobacillus and Enterococcus Capsules combined with Pinaverium Bromide in patients with irritable bowel syndrome and its influence on anorectal dynamics.Method:A total of 80 patients with irritable bowel syndrome admitted to the 971st Hospital of the Chinese People's Liberation Army Navy from June 2020 to December 2022 were selected and divided into two groups according to random number table method,with 40 cases in each group.The control group was treated with Pinaverium Bromide,and the observation group was treated with Live Combined Bifidobacterium,Lactobacillus and Enterococcus Capsules on the basis of the control group.The total effective rate,symptoms and signs integrations(abdominal pain,abdominal bloating and fecal characteristics),anorectal dynamics indexes(resting anal pressure,anal systolic pressure and maximum rectal volume)and quality of life[irritable bowel syndrome-quality of life(IBS-QOL)]of the two groups before and after treatment were compared.Result:The total effective rate of the observation group was significantly higher than that of the control group,the difference was statistically significant(P<0.05).Before treatment,there were no significant differences in symptoms and signs integrations,anorectal dynamics indexes and IBS-QOL scores between the two groups(P>0.05);after treatment,the symptoms and signs integrations and IBS-QOL scores of the observation group were significantly lower than those of the control group,resting anal pressure,anal systolic pressure and maximum rectal volume were significantly higher than those of control group,the differences were statistically significant(P<0.05).Conclusion:Live Combined Bifidobacterium,Lactobacillus and Enterococcus Capsules combined with Pinaverium Bromide has a good effect in patients with irritable bowel syndrome,which can significantly improve the anorectal dynamics of patients,reduce symptoms and signs,and improve the quality of life.
Live Combined Bifidobacterium,Lactobacillus and Enterococcus CapsulesPinaverium BromideIrritable bowel syndromeAnorectal dynamics