Effects of Esketamine Combined with Dextrmetomidine on the Anesthesia Recovery of Preschool Children during Tonsillectomy and Low-temperature Plasma Adenoid Ablation
Objective:To explore the effect of using Esketamine combined with Dexmedetomidine(DEX)on anesthesia recovery in tonsillectomy and low-temperature plasma adenoid ablation of preschool children.Method:A total of 80 children who underwent tonsillectomy and low-temperature plasma adenoid ablation in Yichun People's Hospital from July 2019 to June 2022 were selected,and divided into ED group(n=40)and E group(n=40)by random number table method.Before the anesthesia induction period,E group was given Esketamine anesthesia,and ED group was given Esketamine combined with DEX anesthesia.The restlessness,pain degree,heart rate(HR),anesthesia recovery and adverse reactions of the two groups were compared.Result:The observer's assessment of alertness/sedation scale(OAA/S)score of children in the ED group was higher than that in the E group(P<0.05),and face,legs,activity,crying,corsolability(FLACC)score was lower than that in the E group(P<0.05).In ED group,HR at extubation(T1),5 min after extubation(T2)and 10 min after extubation(T3)were decreased compared to those before anesthesia(T0)(P<0.05);that in T1 period in E group was higher than that in the T0 period(P<0.05),and those in the T2 and T3 periods were lower than those in the T1 period(P<0.05);there were not statistically significant differences between the T2 and T3 periods and the T0 period(P>0.05);and HR at T1,T2,and T3 in ED group were lower than those in E group(P<0.05).The recovery time and the stay time of post-anesthesia care unit(PACU)in ED group were shorter than those in E group(P<0.05).There was not significant difference between ED group(5.00%)and E group(10.00%)in the incidence of adverse reactions(P>0.05).Conclusion:Esketamine combined with DEX anesthesia in tonsillectomy and low-temperature plasma adenoid ablation for preschool children can improve the restlessness and pain,improve the recovery of anesthesia,with higher safety and less impact on HR.
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