首页|内镜逆行胰胆管造影术联合舒肝宁治疗胆总管结石并梗阻性黄疸的效果

内镜逆行胰胆管造影术联合舒肝宁治疗胆总管结石并梗阻性黄疸的效果

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目的:观察并探讨胆总管结石并梗阻性黄疸患者经内镜逆行胰胆管造影术(ERCP)治疗后联合舒肝宁应用的临床效果.方法:选取赣州市赣县区人民医院消化内科于2020年6月—2022年9月收治 80 例胆总管结石并梗阻性黄疸患者作为临床对象.运用随机数字表法进行对照探讨,对照组予以ERCP治疗、联合组予以ERCP联合舒肝宁治疗,各 40 例.比较两组总有效率、症状缓解时间、总住院时间、肝功能[总胆红素(TBIL)、碱性磷酸酶(ALP)、胆碱酯酶(CHE)、丙氨酸氨基转移酶(ALT)].结果:联合组总有效率 90.00%高于对照组的 72.50%,差异有统计学意义(P<0.05).联合组退黄时间、体温恢复正常时间、腹痛缓解时间、总住院时间均短于对照组,差异均有统计学意义(P<0.05).治疗后,两组TBIL、ALP、ALT较治疗前均降低,CHE均升高,且联合组均优于对照组,差异均有统计学意义(P<0.05).结论:ERCP后与舒肝宁联合治疗具有确切效果,能够加快症状缓解,改善肝功能.
Effect of Endoscopic Retrograde Cholangiopancreatography Combined with Shuganning in the Treatment of Choledocholithiasis and Obstructive Jaundice
Objective:To observe and discuss the clinical effect of combined with shuganning after endoscopic retrograde cholangiopancreatography(ERCP)treatment in patients with choledocholithiasis and obstructive jaundice.Method:A total of 80 patients with choledocholithiasis and obstructive jaundice were admitted to the Gastroenterology Department of Ganxian District People's Hospital of Ganzhou from June 2020 to September 2022 were selected as clinical objects.Random number table method was used to conduct a control study,the control group was treated with ERCP,and the combined group was treated with ERCP combined with Shuganning,with 40 cases in each group.Total effective rate,symptom remission time,total hospital stay,liver function[total bilirubin(TBIL),alkaline phosphatase(ALP),cholinesterase(CHE),alanine aminotransferase(ALT)]were compared between the two groups.Result:The total effective rate in the combined group was 90.00%,which was higher than 72.50%in the control group,the difference was statistically significant(P<0.05).The yellowing removal time,temperature recovery normal time,abdominal pain relief time and total hospital stay in combined group were shorter than those in control group,the differences were statistically significant(P<0.05).After treatment,TBIL,ALP and ALT were decreased and CHE were increased in the two groups compared to those before treatment,and those in the combined group were better than those in the control group,the differences were statistically significant(P<0.05).Conclusion:ERCP combined with Shuganning has a definite effect,which can accelerate the relief of symptoms and improve liver function.

CholedocholithiasisObstructive jaundiceShuganningEndoscopic retrograde cholangiopancreatographyLiver function

刘涓涓、陈玲玲

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赣州市赣县区人民医院消化内科 江西 赣州 341100

西安国际医学中心医院胸腔外科 陕西 西安 710100

胆总管结石 梗阻性黄疸 舒肝宁 内镜逆行胰胆管造影术 肝功能

2024

中国医学创新
中国保健协会

中国医学创新

影响因子:1.706
ISSN:1674-4985
年,卷(期):2024.21(3)
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