首页|Solumbra取栓技术在急性脑卒中的应用效果

Solumbra取栓技术在急性脑卒中的应用效果

扫码查看
目的:探究Solumbra取栓技术在急性脑卒中的应用效果.方法:选取赣州市立医院神经外科 2019 年 2 月—2022 年 12 月纳入的 80 例急性脑卒中患者,按照随机抽签法分为观察组与对照组,各40 例.对照组采用常规支架取栓术治疗,观察组采用Solumbra取栓技术治疗.评估两组血管再通率、取栓次数、取栓时间、血清对氧磷酶-1(PON-1)及脑源性神经营养因子(BDNF)、神经功能及并发症.结果:两组血管再通率相比,差异无统计学意义(P>0.05).观察组取栓次数少于对照组;观察组取栓时间短于对照组,差异均有统计学意义(P<0.05).治疗前,两组血清PON-1、BDNF及美国国立卫生研究院卒中量表(NIHSS)评分比较,差异均无统计学意义(P>0.05);治疗后1个月,两组血清PON-1、BDNF均较治疗前升高,且观察组上述指标均高于对照组,两组NIHSS评分均较治疗前降低,且观察组评分低于对照组,差异均有统计学意义(P<0.05).观察组并发症发生率为 5.00%,明显低于对照组的20.00%,差异有统计学意义(P<0.05).结论:Solumbra取栓技术应用于急性脑卒中能够减少取栓次数,缩短取栓时间,提高血清PON-1、BDNF,改善神经功能,安全性相对较高,并发症发生率低.
The Application Effect of Solumbra Thrombectomy Technique in Acute Stroke
Objective:To explore the application effect of Solumbra thrombectomy technique in acute stroke.Method:A total of 80 patients with acute stroke admitted to Department of Neurosurgery,Ganzhou Municipal Hospital from February 2019 to December 2022 were selected and divided into the observation group and the control group according to the random lottery method,with 40 cases in each group.The control group was treated with conventional stent thrombectomy,and the observation group was treated with Solumbra thrombectomy technique.The vascular recanalization rate,thrombectomy times,thrombectomy time,serum paraoxonase-1(PON-1)and brain-derived neurotrophic factor(BDNF),neurological function and complications were evaluated in the two groups.Result:There was no significant difference in the vascular recanalization rate between the two groups(P>0.05).The times of thrombectomy in the observation group was less than that in the control group,the thrombectomy time of the observation group was shorter than that of the control group,the differences were statistically significant(P<0.05).Before treatment,there were no significant differences in serum PON-1,BDNF and national institutes of health stroke scale(NIHSS)scores between the two groups(P>0.05);1 month after treatment,the serum PON-1,BDNF of the two groups were higher than those before treatment,and the above indexes of the observation group were higher than those of the control group,the NIHSS scores of the two groups were lower than those before treatment,and the score of the observation group was lower than that of the control group,the differences were statistically significant(P<0.05).The incidence of complications in the observation group was 5.00%,which was significantly lower than 20.00%in the control group,the difference was statistically significant(P<0.05).Conclusion:Solumbra thrombectomy technique in acute stroke can reduce the times of thrombectomy,shorten the time of thrombectomy,increase serum PON-1 and BDNF,improve neurological function,with relatively high safety and low complication rate.

Solumbra thrombectomy techniqueAcute strokeNeural function

温小华

展开 >

赣州市立医院神经外科 江西 赣州 341099

Solumbra取栓技术 急性脑卒中 神经功能

2024

中国医学创新
中国保健协会

中国医学创新

影响因子:1.706
ISSN:1674-4985
年,卷(期):2024.21(3)
  • 19