The Effect of Early Gastrointestinal Nutrition on Nitrogen Metabolism and Gastrointestinal Function in Coma Patients with Cerebral Trauma
Objective:To investigate the effects of early gastrointestinal nutrition on nitrogen metabolism and gastrointestinal function in coma patients with cerebral trauma.Method:A total of 80 coma patients with cerebral trauma admitted to Changshu Traditional Chinese Medicine Hospital from January 2019 to January 2023 were selected and randomly divided into the control group and the observation group,according to the ratio of 1∶1,with 40 cases in each group.The control group received routine nutritional support,while the observation group received specific early gastrointestinal nutrition support.The nitrogen metabolism indicators,nutritional indicators,gastrointestinal function,immune function indicators,and the total incidence of complications were evaluated in the two groups.Result:After 7 days of intervention,the improvement of nitrogen metabolism in the observation group was more significant,the gastric emptying time,gastrointestinal hormone levels and other gastrointestinal function-related indicators were better than those in the control group,the IgG,IgA,CD4+T cells and CD4+/CD8+ were higher than those in the control group,the differences were statistically significant(P<0.05).In addition,the incidence of complications in the observation group was lower than that in the control group,the difference was statistically significant(P<0.05).Conclusion:Early gastrointestinal nutritional support can improve nitrogen metabolism,gastrointestinal function,and immune function in coma patients with cerebral trauma,which is helpful to promote the recovery of patients and reduce the risk of complications.
Early gastrointestinal nutritionCerebral trauma comaNitrogen metabolismGastrointestinal function