首页|补阳还五汤治疗糖尿病周围神经病变研究进展

补阳还五汤治疗糖尿病周围神经病变研究进展

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作为糖尿病最常见的慢性并发症之一,糖尿病周围神经病变(diabetic peripheral neuropathy,DPN)的发病率与糖尿病病程长短有关.在现代医学中经常使用降糖药联合镇痛药和抗癫痫药物治疗DPN,效果确切,但存在毒副作用大、耐药性高、依从性差等问题.传统医学治疗DPN的特点是辨证论治,运用中药复方,有作用靶点多,疗效机制广和药物毒性低的优点.补阳还五汤是治疗气虚血瘀证型的代表方剂,具有补气活血、通经活络的功效.本文主要从基础方证分析、临床研究和基础研究三个方面探讨补阳还五汤对DPN的治疗作用,旨在研究其治疗DPN的新进展,以期为临床诊疗提供更广阔的思路.
Research Progress of Buyang Huanwu Decoction in the Treatment of Diabetic Peripheral Neuropathy
As one of the most common chronic complications of diabetes,the incidence of diabetic peripheral neuropathy(DPN)is related to the duration of diabetes.In modern medicine,hypoglycemic drugs combined with analgesics and antiepileptic drugs are often used to treat DPN,and the effect is accurate,but there are some problems such as large side effects,high drug resistance and poor compliance.The traditional medicine treatment of DPN is characterized by syndrome differentiation,the use of traditional Chinese medicine compound,has the advantages of many targets,wide therapeutic mechanism and low drug toxicity.Buyang Huanwu Decoction is a representative prescription for the treatment of Qi deficiency and blood stasis syndrome,which has the effect of invigorating qi and activating blood,activating channels and collaterals.This article mainly discusses the therapeutic effect of Buyang Huanwu Decoction on DPN from three aspects:basic prescription analysis,clinical research and basic research,aiming to study the new progress of its treatment of DPN,in order to provide a broader idea for clinical diagnosis and treatment.

Diabetic peripheral neuropathyBuyang Huanwu DecoctionQi deficiency and blood stasisChinese herbal compound

徐金添、伊桐凝

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辽宁中医药大学研究生学院 辽宁 沈阳 110847

辽宁中医药大学附属医院科研处 辽宁 沈阳 110033

糖尿病周围神经病变 补阳还五汤 气虚血瘀 中药复方

2024

中国医学创新
中国保健协会

中国医学创新

影响因子:1.706
ISSN:1674-4985
年,卷(期):2024.21(3)
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