Effect of Retrograde Intrarenal Surgery on Oxidative Stress Reaction in Patients with Renal Calculus
Objective:To investigate the effect of retrograde intrarenal surgery(RIRS)on oxidative stress reaction in patients with renal calculus.Method:A total of 80 patients with renal calculus admitted to Yichun Hospital of Traditional Chinese Medicine from July 2021 to December 2022 were selected and divided into two groups according to random number table method,with 40 cases in each group.The observation group was treated with RIRS,and the control group was treated with microchannel percutaneous nephrolithotripsy(mPCNL).Perioperative period indexes,primary stone purification rate,oxidative stress reaction[superoxide dismutase(SOD),cortisol(Cor),malondialdehyde(MDA),glutathione peroxidase(GSH-Px)]and complication rate were compared between the two groups.Result:The hospital stay of the observation group was shorter than that of the control group,and the primary stone purification rate of the observation group was higher than that of the control group,the differences were statistically significant(P＜0.05).1 day after surgery,MDA and Cor in both groups were higher than those before surgery,but those in the observation group were lower than those in the control group,SOD and GSH-Px in both groups were lower than those before surgery,but those in the observation group were higher than those in the control group,the differences were statistically significant(P＜0.05).There were no significant difference in operation time and total complication rate between the two groups(P＞0.05).Conclusion:Both RIRS and mPCNL can effectively treat patients with renal calculus with high safety,but RIRS can shorten the hospital stay of patients,effectively improve the primary stone purification rate of patients,and alleviate their oxidative stress reaction.
万方数据
维普
