Effects of Dulaglutide Injection Combined with Low-carbohydrate Breakfast Diet Therapy on Glucose and Lipid Metabolism Disorders in Elderly Patients with Diabetes Mellitus
Objective:To investigate the effect of Dulaglutide Injection combined with low-carbohydrate breakfast diet therapy on glucose and lipid metabolism disorders in elderly diabetic patients.Method:A total of 84 elderly patients with diabetes mellitus who came to the Endocrinology Department of Shanxian Central Hospital from January 2021 to January 2023 were divided into the control group(42 cases)and the experimental group(42 cases)by random number table method.Both groups were treated with conventional drug therapy.On this basis,the control group was treated with low-carbohydrate breakfast diet therapy,the experimental group was treated with Dulaglutide Injection on the basis of the treatment of the control group.The course of treatment was 3 months.The glucose metabolism level,blood lipid index level,body mass index(BMI),and insulin level were compared between the two groups before and after treatment.Result:After treatment,fasting plasma glucose(FPG),2-hour postprandial plasma glucose(2 h PG)and glycosylated hemoglobin A1c(HbA1c)in the two groups were significantly lower than those before treatment,and those in the experimental group were lower than those in the control group(P<0.05).The low density lipoprotein cholesterol(LDL-C),total cholesterol(TC)and triglyceride(TG)in the experimental group were lower than those in the control group(P<0.05),while the high density lipoprotein cholesterol(HDL-C)in the experimental group was higher than that in the control group(P<0.05).The BMI,fasting insulin(FINS)and 2-hour postprandial insulin in the experimental group were lower than those in the control group(P<0.05).Conclusion:Dulaglutide Injection combined with low-carbohydrate breakfast diet therapy has a good therapeutic effect on elderly diabetes mellitus,which can effectively improve glucose and lipid metabolism and insulin function,and reduce blood glucose and body weight.
Dulaglutide InjectionLow-carbohydrateBreakfast diet therapyThe elderlyDiabetes mellitusGlucose and lipid metabolismBody mass indexInsulin