首页|度拉糖肽注射液配合低碳水化合物早餐饮食疗法对老年糖尿病患者糖脂代谢紊乱的影响

度拉糖肽注射液配合低碳水化合物早餐饮食疗法对老年糖尿病患者糖脂代谢紊乱的影响

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目的:探究度拉糖肽注射液配合低碳水化合物早餐饮食疗法对老年糖尿病患者糖脂代谢紊乱的影响.方法:采用随机数字表法将 84 例 2021 年 1 月—2023 年 1 月来单县中心医院内分泌科就诊的老年糖尿病患者分为对照组(42 例)和试验组(42 例),两组均予以常规药物治疗,在此基础上,对照组予以低碳水化合物早餐饮食疗法治疗,试验组则在对照组治疗基础上加用度拉糖肽注射液治疗,疗程均为 3 个月,对比两组治疗前后糖代谢水平、血脂指标水平、体重指数(BMI)、胰岛素水平.结果:经治疗后,两组空腹血糖(FPG)、餐后 2 h血糖(2 h PG)及糖化血红蛋白(HbA1c)均较于治疗前明显下降,且试验组均低于对照组(P<0.05);试验组低密度脂蛋白胆固醇(LDL-C)、总胆固醇(TC)、甘油三酯(TG)均比对照组低(P<0.05),而高密度脂蛋白胆固醇(HDL-C)比对照组高(P<0.05);试验组BMI、空腹胰岛素(FINS)、餐后 2 h胰岛素均低于对照组(P<0.05).结论:采用度拉糖肽注射液配合低碳水化合物早餐饮食疗法对老年糖尿病治疗具有较好的效果,能够有效改善糖脂代谢异常和胰岛素功能,降低血糖与体质量.
Effects of Dulaglutide Injection Combined with Low-carbohydrate Breakfast Diet Therapy on Glucose and Lipid Metabolism Disorders in Elderly Patients with Diabetes Mellitus
Objective:To investigate the effect of Dulaglutide Injection combined with low-carbohydrate breakfast diet therapy on glucose and lipid metabolism disorders in elderly diabetic patients.Method:A total of 84 elderly patients with diabetes mellitus who came to the Endocrinology Department of Shanxian Central Hospital from January 2021 to January 2023 were divided into the control group(42 cases)and the experimental group(42 cases)by random number table method.Both groups were treated with conventional drug therapy.On this basis,the control group was treated with low-carbohydrate breakfast diet therapy,the experimental group was treated with Dulaglutide Injection on the basis of the treatment of the control group.The course of treatment was 3 months.The glucose metabolism level,blood lipid index level,body mass index(BMI),and insulin level were compared between the two groups before and after treatment.Result:After treatment,fasting plasma glucose(FPG),2-hour postprandial plasma glucose(2 h PG)and glycosylated hemoglobin A1c(HbA1c)in the two groups were significantly lower than those before treatment,and those in the experimental group were lower than those in the control group(P<0.05).The low density lipoprotein cholesterol(LDL-C),total cholesterol(TC)and triglyceride(TG)in the experimental group were lower than those in the control group(P<0.05),while the high density lipoprotein cholesterol(HDL-C)in the experimental group was higher than that in the control group(P<0.05).The BMI,fasting insulin(FINS)and 2-hour postprandial insulin in the experimental group were lower than those in the control group(P<0.05).Conclusion:Dulaglutide Injection combined with low-carbohydrate breakfast diet therapy has a good therapeutic effect on elderly diabetes mellitus,which can effectively improve glucose and lipid metabolism and insulin function,and reduce blood glucose and body weight.

Dulaglutide InjectionLow-carbohydrateBreakfast diet therapyThe elderlyDiabetes mellitusGlucose and lipid metabolismBody mass indexInsulin

刘效荣、谢明蕊、王凤云

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单县中心医院内分泌科 山东 单县 274300

度拉糖肽注射液 低碳水化合物 早餐饮食疗法 老年 糖尿病 糖脂代谢 体重指数胰岛素

2024

中国医学创新
中国保健协会

中国医学创新

影响因子:1.706
ISSN:1674-4985
年,卷(期):2024.21(4)
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