Comparison of the Effect of Volume Target Ventilation and High Frequency Oscillation Ventilation in the Treatment of Neonatal Respiratory Distress Syndrome
Objective:To compare and study the therapeutic effects of volume target ventilation and high frequency oscillation ventilation in neonatal respiratory distress syndrome.Method:A total of 100 children with neonatal respiratory distress syndrome treated in Zhanjiang Maternal and Child Health and Family Planning Service Center from June 2021 to June 2023 were randomly divided into control group and study group,with 50 cases in each group.The study group adopted high frequency oscillation ventilation mode(high frequency mechanical ventilation + target tidal volume),and the control group adopted volume target ventilation mode.Arterial blood gas indexes,the incidence of complications,mortality,invasive ventilation time,oxygen therapy time and hospital stay were compared between the two groups.Result:Invasive ventilation time,oxygen therapy time and hospital stay in the study group were shorter than those in the control group(P<0.05).There was no significant difference in mortality between the two groups(0 vs 8.00%)(P>0.05).There were no significant differences in blood partial pressure of oxygen,oxyhemoglobin saturation,pH value and partial pressure of carbon dioxide between the two groups before intervention(P>0.05);after 48 h of intervention,the blood partial pressure of oxygen,oxyhemoglobin saturation and pH value of the study group were higher than those before intervention and control group,and the partial pressure of carbon dioxide of the study was lower than those before intervention and control group(P<0.05).The incidence of complications of the study group(10.00%)was lower than that of the control group(36.96%)(P<0.05).Conclusion:High frequency oscillation ventilation mode can effectively improve the arterial blood gas indexes of children with neonatal respiratory distress syndrome,shorten the recovery time and reduce the occurrence of various complications.
Volume target ventilationHigh frequency oscillation ventilationNeonatal respiratory distress syndrome
国家科技期刊平台
NSTL
万方数据
维普
