寿胎丸加减治疗先兆流产合并阴道出血的临床效果
Clinical Effect of Shoutai Pills Plus and Minus Treatment of Threatened Abortion Complicated with Vaginal Bleeding
肖慧欣 1刘雅倩1
作者信息
- 1. 会昌县妇幼保健院妇产科 江西 会昌 342600
- 折叠
摘要
目的:探究寿胎丸加减治疗先兆流产合并阴道出血的临床效果.方法:选取 2020 年 10 月—2022 年 10 月会昌县妇幼保健院收治的 66 例先兆流产合并阴道出血患者,根据随机数字表法分为试验组和对照组,各 33 例.对照组给予地屈孕酮和黄体酮治疗,试验组在对照组基础上给予寿胎丸加减治疗.对比两组临床疗效、中医症状积分、孕酮、雌二醇、β-人绒毛膜促性腺激素及免疫功能、妊娠结局.结果:治疗 14 d,两组阴道出血、下腹坠胀、腰酸及腹痛积分均下降,试验组均低于对照组,差异均有统计学意义(P<0.05).试验组总有效率高于对照组,差异有统计学意义(P<0.05).治疗 14 d,两组孕酮、雌二醇、β-人绒毛膜促性腺激素水平均升高,试验组均高于对照组,差异均有统计学意义(P<0.05).治疗 14 d,两组CD4+、CD4+/CD8+水平较治疗前均升高,CD8+水平较治疗前均降低,且试验组CD4+、CD4+/CD8+水平均高于对照组,CD8+水平低于对照组,差异均有统计学意义(P<0.05).试验组足月分娩率为 87.88%,高于对照组的 66.67%,差异有统计学意义(P<0.05);两组死胎、流产、早产率比较,差异均无统计意义(P>0.05).结论:在地屈孕酮和黄体酮治疗基础上,寿胎丸加减治疗先兆流产合并阴道出血效果较好,有利于改善临床症状、孕酮、雌二醇、β-人绒毛膜促性腺激素及妊娠结局.
Abstract
Objective:To explore the clinical effect of addition and reduction of Shoutai Pills in the treatment of threatened abortion complicated with vaginal bleeding.Method:From October 2020 to October 2022,66 patients with threatened abortion and vaginal bleeding were enrolled in Huichang County Maternal and Child Health Care Hospital and were divided into the experimental group and the control group according to the random number table method,with 33 cases each.The control group was treated with Dydrogesterone and Progesterone,and the experimental group was given Shoutai Pills plus and minus treatment on the basis of the control group.The clinical efficacy,TCM symptom score,progesterone,estradiol,β-human chorionic gonadotropin and immune function,and pregnancy outcomes in two groups were compared.Result:After 14 days of treatment,the scores of vaginal bleeding,lower abdominal distension,backache and abdominal pain decreased in two groups,and those in the experimental group were lower than those in the control group,the differences were statistically significant(P<0.05).The total effective rate of the experimental group was higher than that of the control group,the difference was statistically significant(P<0.05).After 14 days of treatment,the levels of progesterone,estradiol and β-human chorionic gonadotropin in two groups were increased,and those in the experimental group were higher than those in the control group,the differences were statistically significant(P<0.05).After 14 days of treatment,the CD4+ and CD4+/CD8+ levels in two groups were higher than those before treatment,and the CD8+ levels were lower than those before treatment,and the CD4+ and CD4+/CD8+ levels in the experimental group were higher than those in the control group,and the CD8+ level was lower than that in the control group,the differences were statistically significant(P<0.05).The full-term delivery rate in the experimental group was 87.88%,which was higher than 66.67%in the control group,the difference was statistically significant(P<0.05).There were no statistically significant differences in the rates of stillbirth,abortion and premature birth between the two groups(P>0.05).Conclusion:On the basis of Dydrogesterone and Progesterone treatment,the Shoutai Pills plus and minus has a good therapeutic effect on threatened abortion combined with vaginal bleeding,which is beneficial for improving clinical symptoms,progesterone,β-human chorionic gonadotropin and pregnancy outcomes.
关键词
寿胎丸/先兆流产/阴道出血/临床症状/妊娠结局Key words
Shoutai Pills/Threatened abortion/Vaginal bleeding/Clinical symptoms/Pregnancy outcome引用本文复制引用
出版年
2024
国家科技期刊平台
NSTL
维普
万方数据