Clinical Effect of Shoutai Pills Plus and Minus Treatment of Threatened Abortion Complicated with Vaginal Bleeding
Objective:To explore the clinical effect of addition and reduction of Shoutai Pills in the treatment of threatened abortion complicated with vaginal bleeding.Method:From October 2020 to October 2022,66 patients with threatened abortion and vaginal bleeding were enrolled in Huichang County Maternal and Child Health Care Hospital and were divided into the experimental group and the control group according to the random number table method,with 33 cases each.The control group was treated with Dydrogesterone and Progesterone,and the experimental group was given Shoutai Pills plus and minus treatment on the basis of the control group.The clinical efficacy,TCM symptom score,progesterone,estradiol,β-human chorionic gonadotropin and immune function,and pregnancy outcomes in two groups were compared.Result:After 14 days of treatment,the scores of vaginal bleeding,lower abdominal distension,backache and abdominal pain decreased in two groups,and those in the experimental group were lower than those in the control group,the differences were statistically significant(P<0.05).The total effective rate of the experimental group was higher than that of the control group,the difference was statistically significant(P<0.05).After 14 days of treatment,the levels of progesterone,estradiol and β-human chorionic gonadotropin in two groups were increased,and those in the experimental group were higher than those in the control group,the differences were statistically significant(P<0.05).After 14 days of treatment,the CD4+ and CD4+/CD8+ levels in two groups were higher than those before treatment,and the CD8+ levels were lower than those before treatment,and the CD4+ and CD4+/CD8+ levels in the experimental group were higher than those in the control group,and the CD8+ level was lower than that in the control group,the differences were statistically significant(P<0.05).The full-term delivery rate in the experimental group was 87.88%,which was higher than 66.67%in the control group,the difference was statistically significant(P<0.05).There were no statistically significant differences in the rates of stillbirth,abortion and premature birth between the two groups(P>0.05).Conclusion:On the basis of Dydrogesterone and Progesterone treatment,the Shoutai Pills plus and minus has a good therapeutic effect on threatened abortion combined with vaginal bleeding,which is beneficial for improving clinical symptoms,progesterone,β-human chorionic gonadotropin and pregnancy outcomes.
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