Research Progress on Brain Function Mechanism of Onset of Depressive Disorder
Depressive disorder is a mental disease caused by many reasons,and its pathogenesis has not been fully defined.This paper summarizes the pathogenesis of depression disorder from the perspective of brain function and structure,and finds that depression disorder is closely related to brain regions such as hippocampus and prefrontal cortex.The decrease in the area and volume of hippocampus and prefrontal cortex and the damage of neuronal morphology and ultrastructure are the anatomical and structural basis of depression disorder.Decreased blood flow,decreased metabolism,abnormal brain network connectivity and imbalance of neuroelectrophysiological activity are the brain functional mechanisms of depression disorder.