小窝蛋白1与脑梗死相关性研究进展
Research Progress in the Correlation between Caveolin-1 and Cerebral Infarction
李晓岚 1黄建敏2
作者信息
- 1. 右江民族医学院研究生学院 广西 百色 533000
- 2. 右江民族医学院附属医院神经内科 广西 百色 533000
- 折叠
摘要
小窝蛋白 1(caveolin-1,Cav-1)是小窝中的一种支架蛋白和胆固醇结合蛋白,是细胞膜穴样内陷的主要结构成分,在脂质转运、细胞生长分化、血管生成等方面有着重要的作用.Cav-1 在中枢神经系统的内皮细胞、周细胞、星形胶质细胞等许多细胞中表达.现有研究表明Cav-1 与多种中枢神经系统疾病之间存在密切联系,本文简要概述Cav-1 与脑梗死的关系.
Abstract
Caveolin-1(Cav-1)is a scaffold protein and cholesterol binding protein in caveolae.It is the main structural component of cell membrane hole-like invagination,and plays an important role in lipid transport,cell growth and differentiation,angiogenesis and other aspects.Cav-1 is expressed in many other cells,including endothelial cells,pericytes,and astrocytes of the central nervous system.Existing studies indicate a close link between Cav-1 and multiple central nervous system diseases,which provide a brief overview of the relationship between Cav-1 and cerebral infarction.
关键词
小窝蛋白1/脑梗死/动脉粥样硬化/血管生成Key words
Caveolin-1/Cerebral infarction/Atherosclerosis/Angiogenesis引用本文复制引用
出版年
2024