Research Progress of Topical Small Molecule Drugs in Treating Alopecia Areata
Alopecia areata(AA)is a common autoimmune disease of hair follicles,the application of topical drugs plays an important role in mild to moderate AA.Traditional topical drugs such as Glucocorticoids,Minoxidil,topical contact irritants,etc.lack satisfactory efficacy for some patients,and long-term use is limited by side effects.With the further understanding of the pathogenesis of AA,small molecule drugs such as JAK inhibitors and phosphodiesterase inhibitors have brought available treatment for alopecia areata.More researches are needed to prove its efficacy and safety.
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