首页|腹腔镜联合胆道镜治疗左肝内胆管结石合并胆总管结石的安全性及有效性分析

腹腔镜联合胆道镜治疗左肝内胆管结石合并胆总管结石的安全性及有效性分析

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目的:研究腹腔镜联合胆道镜治疗左肝内胆管结石同时合并胆总管结石的效果,同时探讨安全性及有效性.方法:选取萍乡市人民医院肝胆胰外科 2018 年 1 月—2022 年 12 月收治的左肝内胆管结石合并胆总管结石患者180例作为研究对象,按照随机数字表法分为观察组(90例)和对照组(90例).观察组的患者使用腹腔镜左肝切除及胆道镜取石,对照组的患者采取常规开腹左肝切除及胆道镜取石,比较两组患者相关手术时间、术中出血量、术后患者结石残留率、并发症发生率,比较两组患者术后下地时间、胃肠道功能恢复时间、术后住院时间及肝功能变化等指标.结果:观察组的手术时间长于对照组,其术中出血量少于对照组,术后下地时间、术后胃肠道功能恢复时间、术后住院时间均明显短于对照组(P<0.05).观察组术后丙氨酸氨基转移酶(ALT)、天冬氨酸氨基转移酶(AST)和总胆红素(TBIL)的水平均明显低于对照组(P<0.05).观察组围手术期切口感染、胆漏、胆道出血及肺部感染的发生率为6.67%(6/90),显著低于对照组的 16.67%(15/90)(P<0.05).术后随访显示,观察组结石残留率为 3.33%(3/90),对照组为 2.22%(2/90),两组间结石残留率差异无统计学意义(P>0.05).结论:腹腔镜肝切除联合胆道镜取石治疗左肝内胆管结石合并胆总管结石可减少手术创伤,加快患者康复,改善肝功能,减少术后并发症,取石效果好,安全可靠.
Analysis of the Safety and Effectiveness of Laparoscopy Combined with Choledochoscope in the Treatment of Left Intrahepatic Bile Duct Stones with Choledocholithiasis
Objective:To study the effect of laparoscopy combined with choledochoscope in the treatment of left intrahepatic bile duct stones with choledocholithiasis,and to explore the safety and effectiveness.Method:A total of 180 patients with left intrahepatic bile duct stones with choledocholithiasis in Department of Hepatobiliary and Pancreatic Surgery of Pingxiang People's Hospital from January 2018 to December 2022 were selected for the study and divided into an observation group(90 cases)and a control group(90 cases)according to the random number table method.Patients in the observation group were treated with laparoscopic left hepatectomy combined with choledochoscopy exploration and stone removal,while patients in the control group were treated with conventional open left hepatectomy combined with choledochoscopy exploration.The relevant surgical time,intraoperative blood loss,postoperative stone residue rate,and incidence of complications between two groups of patients were compared.The postoperative time to the ground,gastrointestinal function recovery time,postoperative hospital stay and liver function changes between the two groups of patients were compared.Result:Surgery time in the observation group was longer than that in the control group,and the intraoperative blood loss was less than that of the control group,the postoperative time to the ground,recovery time of gastrointestinal function and hospitalization time were significantly shorter than those of the control group(P<0.05).The postoperative levels of alanine aminotransferase(ALT),aspartate aminotransferase(AST)and total bilirubin(TBIL)in the observation group were significantly lower than those in the control group(P<0.05).The incidence of perioperative incision infection,bile leakage,biliary bleeding and pulmonary infection in the observation group was 6.67%(6/90),significantly lower than 16.67%(15/90)in the control group(P<0.05).Postoperative follow-up showed that the residual rate of stones in the observation group was 3.33%(3/90),while in the control group it was 2.22%(2/90).There was no statistically significant difference in the residual rate of stones between the two groups(P>0.05).Conclusion:Laparoscopic hepatectomy combined with choledochoscope exploration and lithotomy in the treatment of left intrahepatic bile duct stones with choledocholithiasis can reduce the surgical trauma,promote the rehabilitation of patients,improve the liver function of patients,reduce the occurrence of postoperative complications,and the lithotomy effect and safety are reliable.

LaparoscopyCholedochoscopeIntrahepatic bile duct stonesCholedocholithiasis

叶国华、姜继豪、杨阳

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萍乡市人民医院肝胆胰外科 江西 萍乡 337000

腹腔镜 胆道镜 肝内胆管结石 胆总管结石

江西省卫生健康委科技项目

SKJP220228105

2024

中国医学创新
中国保健协会

中国医学创新

影响因子:1.706
ISSN:1674-4985
年,卷(期):2024.21(6)
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