Application Evaluation of Non-invasive Ventilation Combined with Respiration Training in Patients with AECOPD Complicated with Respiratory Failure
Objective:To explore the effect of non-invasive ventilation combined with respiration training on patients with acute exacerbation of chronic obstructive pulmonary disease(AECOPD)complicated with respiratory failure.Method:A total of 67 patients with AECOPD complicated with respiratory failure admitted to Department of Emergency,Affiliated Hospital of Guilin Medical University from February 2019 to February 2022 were prospectively included,and the patients were divided into two groups according to random number table method.The control group(n=33)received intermittent non-invasive ventilation treatment,and the observation group(n=34)was supplemented with active respiration training(including upper limb elastic band impedance training,pursed-lip abdominal breathing,and the use of respiratory trainer)on the basis of the control group.The weaning success rate within 2 days and the incidence of adverse reactions were recorded between the two groups,and the oxygenation index(OI),arterial partial pressure of carbon dioxide(PaCO2),modified medical research council(mMRC)dyspnoea questionnaire grade,respiratory rate(RR)and spontaneous breathing tidal volume were compared between the two groups.Result:The weaning success rate within 2 days was 60.6%in control group and 82.4%in observation group,and the weaning success rate in observation group was higher than that in control group(P<0.05).The incidences of expectoration inertia and respiratory fatigue in observation group were lower than those in control group(P<0.05).Compared with those before treatment,the OI and PaCO2 of the two groups were significantly improved after 2 days of treatment,the differences were statistically significant(P<0.05).After 2 days of treatment,PaCO2 in the observation group was lower than that in the control group(P<0.05),but there was no significant difference in OI between the two groups(P>0.05).Compared with those before treatment,after 2 days of treatment,mMRC dyspnoea questionnaire grade and RR of the two groups were significantly decreased,and the spontaneous breathing tidal volume were significantly increased,the differences were statistically significant(P<0.05).After 2 days of treatment,there were no significant differences in mMRC dyspnoea questionnaire grade and RR between the two groups(P>0.05),but the spontaneous breathing tidal volume in the observation group was significantly higher than that in the control group(P<0.05).Conclusion:Non-invasive ventilation combined with respiration training for patients with AECOPD complicated with respiratory failure can effectively improve respiratory muscle fatigue,increase lung ventilation,and improve weaning success rate.
Non-invasive ventilationRespiration trainingAcute exacerbation of chronic obstructive pulmonary diseaseRespiratory failure
万方数据
维普
