Influence of Limited Fluid Resuscitation on Multisystem Organ Function and Oxygen Supply and Consumption of Patients with Hemorrhagic Shock
Objective:To investigate and observe the influence of limited fluid resuscitation on multisystem organ function and oxygen supply and consumption of patients with hemorrhagic shock.Method:A total of 80 patients with hemorrhagic shock in Yong'an Municipal Hospital from March 2019 to March 2022 were divided into the control group and the observation group with 40 cases in each group by the method of random number table.The control group was treated with routine fluid resuscitation,the observation group was treated with limited fluid resuscitation.Then the liver function indexes[aspartate transaminase(AST)and alanine transaminase(ALT)],renal function indexes[blood urea nitrogen(BUN)and creatinine(Cr)],myocardial injury indexes[creatine kinase(CK)and creatine kinase isoenzymes(CK-MB)],oxygen supply and consumption indexes[oxygen supply(DO2),oxygen supply index(DO2I),oxygen consumption(VO2),oxygen consumption index(VO2I)]of two groups before and after treatment were compared.Result:The liver function indexes,renal function indexes and myocardial injury indexes,oxygen supply and consumption indexes of two groups before treatment were compared,the differences were not statistically significant(P>0.05),the liver function indexes,renal function indexes and myocardial injury indexes of two groups at 1st,2nd and 6th hour after treatment increased,while those of observation group were all lower than those of control group,the oxygen supply and consumption indexes increased,and those of observation group were significantly higher than those of control group,the differences were statistically significant(P<0.05).Conclusion:The limited fluid resuscitation can effectively control the multisystem organ dysfunction of patients with hemorrhagic shock,and its influence for oxygen supply and consumption is more active,so its application value in the patients with hemorrhagic shock is relatively higher.
Limited fluid resuscitationHemorrhagic shockMultisystem organ functionOxygen supplyOxygen consumption