The Clinical Value of Erythrocyte Sedimentation Rate Combined with hs-CRP Level in Predicting Prognosis of Patients with Spinal Tuberculosis
Objective:To analyze the clinical value of erythrocyte sedimentation rate(ESR)combined with hypersensitive C reactive protein(hs-CRP)in predicting the prognosis of patients with spinal tuberculosis.Method:Clinical data of 102 patients with spinal tuberculosis admitted to Yangzhou Third People's Hospital from January 2016 to January 2022 were retrospectively analyzed,and 60 healthy people who underwent physical examination in our hospital were recruited and recorded as study group and control group respectively.The levels of ESR and hs-CRP in the two groups were compared,and the clinical data of the study group were analyzed,the independent factors affecting the prognosis of patients with spinal tuberculosis were analyzed by multivariate logistic regression,the predictive value of ESR and hs-CRP in the prognosis of patients with spinal tuberculosis was evaluated by receiver operating characteristic(ROC)curve.Result:The levels of ESR and hs-CRP in the study group were higher than those in the control group(P<0.05).The good prognosis was 90.20%,and the poor prognosis was 9.80%of patients in the study group.There were no statistical significance in age,gender,body mass index(BMI),diabetes,hypertension,serum creatinine(Cr)and albumin between patients with good and poor prognosis of spinal tuberculosis(P>0.05);there were statistically significant differences in ESR and hs-CRP levels(P<0.05).Logistic regression analysis was performed,and the results of multivariate analysis showed that ESR,hs-CRP were the risk factors for prognosis of patients with spinal tuberculosis(P<0.05).ESR and hs-CRP combined levels had the best prognostic effect on prognosis of patients with spinal tuberculosis,and the area under the curve(AUC)(0.771)was higher than 0.713 and 0.719 individual predicted(Z=3.526,P=0.027;Z=3.507,P=0.032),the sensitivity and specificity were 86.54%and 79.02%,respectively.Conclusion:The ESR and hs-CRP levels in patients with spinal tuberculosis are abnormal,and the ESR and hs-CRP levels in patients with poor prognosis are higher than those in patients with good prognosis.The value of ESR and hs-CRP levels in the prognosis of patients with spinal tuberculosis is high.
Erythrocyte sedimentation rateHypersensitive C reactive proteinTuberculosis of the spineSensitivitySpecificityGood prognosis
万方数据
维普
