Research Progress of Ferroptosis in Gastrointestinal Tumors
Gastrointestinal cancer is a common malignant tumor,and the research on its treatment and prognosis has attracted much attention.As a new type of cell death,ferroptosis has been paid more and more attention in the study of digestive tract tumors in recent years.Ferroptosis is a way of cell death that is different from apoptosis,pyroptosis,autophagy and non-programmed necrosis-related cell death,and its role and mechanism in digestive tract tumors have attracted extensive interest from researchers.Ferroptosis exists in inflammation,ischemia-reperfusion injury,acute kidney injury and tumor,and plays an important role in the process of disease.The study of ferroptosis in digestive tract tumors has important clinical significance,which is of great significance for understanding the pathogenesis of digestive tract tumors and developing new treatment methods.Therefore,this review aims to summarize and analyze the research of ferroptosis in digestive tract tumors,in order to provide theoretical support for the research in related fields.