首页|自体角膜缘干细胞移植术联合翼状胬肉切除术治疗翼状胬肉患者效果

自体角膜缘干细胞移植术联合翼状胬肉切除术治疗翼状胬肉患者效果

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目的:探讨自体角膜缘干细胞移植术、翼状胬肉切除术联合治疗翼状胬肉患者的效果.方法:从南平市第二医院 2021 年 1 月—2023 年 1 月诊治的翼状胬肉患者中选择 80 例为观察对象,根据住院号单双数将其分为两组,每组 40 例,其中用翼状胬肉切除术治疗的为对照组,自体角膜缘干细胞移植术、翼状胬肉切除术治疗的为研究组.对比两组术前后的裸眼视力、屈光度及泪膜破裂时间(BUT)、泪液分泌试验(SIT)结果数值,统计两组并发症情况.结果:研究组术后裸眼视力与BUT、SIT结果数值均大于对照组,差异均有统计学意义(P<0.05);研究组屈光度小于对照组,差异有统计学意义(P<0.05);研究组并发症发生率低于对照组,差异有统计学意义(P<0.05).结论:在翼状胬肉患者中联合应用翼状胬肉切除术、自体角膜缘干细胞移植术进行治疗,术后能够改善裸眼视力及屈光度,有利于泪膜功能恢复正常,且安全性较高.
Effect of Autologous Limbal Stem Cell Transplantation Combined with Pterygium Excision in Treatment of Pterygium Patients
Objective:To investigate the effect of limbal stem cell transplantation combined with pterygium excision in treatment of pterygium patients.Method:Eighty patients with pterygium treated in No.2 Hospital of Nanping City from January 2021 to January 2023 were selected as the observation objects and divided into two groups according to the number of hospitalization numbers,with 40 cases in each group.Among which the control group was treated with pterygium resection and the study group was treated with autologous limbal stem cell transplantation and pterygium resection.The naked eye visual acuity,diopter,results of breakup time of tear film(BUT)and Schirmer test(SIT)of the two groups were compared before and after surgery,and the complications of the two groups were analyzed.Result:The naked eye visual acuity,BUT and SIT results of the study group were higher than those of the control group,the differences were statistically significant(P<0.05).The diopter of the study group was lower than that of the control group,the difference was statistically significant(P<0.05).The complication rate of the study group was lower than that of the control group,the difference was statistically significant(P<0.05).Conclusion:Combined pterygium excision and autologous limbal stem cell transplantation in patients with pterygium can improve naked eye vision and diopter after surgery,and is beneficial to restore normal tear film function,with high safety.

Limbal stem cell autotransplantationPterygium excisionPterygium

段芳芝、杨得军

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南平市第二医院眼科 福建 南平 354200

自体角膜缘干细胞移植术 翼状胬肉切除术 翼状胬肉

2024

中国医学创新
中国保健协会

中国医学创新

影响因子:1.706
ISSN:1674-4985
年,卷(期):2024.21(7)
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