首页|延迟断脐与断脐方式选择对胎龄小于32周早产儿临床结局的影响

延迟断脐与断脐方式选择对胎龄小于32周早产儿临床结局的影响

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目的:探讨延迟断脐与断脐方式选择对胎龄小于 32 周早产儿临床结局的影响.方法:选取2019 年 10 月—2022 年 10 月中国人民解放军总医院第七医学中心收治的 126 例早产儿,随机均分为延迟脐带结扎(deferred cord clamping,DCC)组、脐带挤压(umbilical cord milking,UCM)组、常规组,每组 42 例.比较三组早产儿产后血红蛋白与红细胞压积、不良事件发生率、平均输血量、光疗时间、产后胎盘残余血量、脐部残端脱落时间.结果:与常规组比较,UCM组、DCC组产后 1 h、1 周的血红蛋白、红细胞压积均明显更高(P<0.05),UCM组、DCC组产后 1 h、1 周的血红蛋白、红细胞压积差异均无统计学意义(P>0.05).UCM组、DCC组贫血事件的发生率均显著低于常规组(P<0.05),三组颅内出血、病理性黄疸、支气管肺发育不良的发生率差异均无统计学意义(P>0.05).三组输血量、光疗时间、产后胎盘残余血量、脐部残端脱落时间差异均有统计学意义(P<0.05).结论:断脐方式对胎龄<32 周早产儿的临床结局有重要影响,与常规断脐方式比较,采取延迟断脐或脐带挤压方式,有助于促进血液从胎盘到新生儿的转移,改善产后血红蛋白与红细胞压积,降低贫血风险,缩短脐部残端脱落时间.
Effect of Delayed Umbilical Cord and Choice of Umbilical Cord Weaning Mode on Clinical Outcome of Premature Infants with Gestational Age Less than 32 Weeks
Objective:To investigate the effect of delayed umbilical cord and the choice of umbilical cord weaning method on the clinical outcome of preterm infants less than 32 weeks of gestational age.Method:A total of 126 preterm infants admitted to the Seventh Medical Center of PLA General Hospital from October 2019 to October 2022 were selected and equally divided into deferred cord clamping(DCC)group,umbilical cord milking(UCM)group and conventional group,with 42 cases in each group.The postnatal haemoglobin and hematocrit,incidence of adverse events,mean blood transfusion,time to phototherapy,postnatal placental residual blood volume and time to detachment of umbilical stump were compared among the three groups of preterm infants.Result:Compared with the conventional group,haemoglobin and hematocrit were significantly higher in the UCM group and DCC group at 1 h and 1 week postpartum(P<0.05),there were no significant differences in hemoglobin and hematocrit in UCM group and DCC group at 1 h and 1 week postpartum(P>0.05).The incidences of anaemic events in the UCM group and DCC group were significantly lower than that in the conventional group(P<0.05),there were no significant differences in the incidences of intracranial hemorrhage,pathological jaundice and bronchopulmonary dysplasia among the three groups(P>0.05).There were significant differences in blood transfusion volume,phototherapy time,placental residual blood volume and umbilical stump shedding time among the three groups(P<0.05).Conclusion:The method of umbilical cord weaning has an important impact on the clinical outcome of preterm infants born at gestational age<32 weeks.Compared with the conventional method of umbilical cord weaning,adopting delayed umbilical cord weaning or umbilical cord milking helps to facilitate the transfer of blood from the placenta to the newborn,improve postnatal haemoglobin and hematocrit,reduce the risk of anaemia and shorten the time to detach the umbilical cord stump.

Preterm infantDelayed umbilical cordUmbilical cord milkingMode of umbilical cord weaningClinical outcome

赵德荣

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中国人民解放军总医院第七医学中心产房 北京 100700

早产儿 延迟断脐 脐带挤压 断脐方式 临床结局

2024

中国医学创新
中国保健协会

中国医学创新

影响因子:1.706
ISSN:1674-4985
年,卷(期):2024.21(8)
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