首页|有氧运动联合抗阻运动对妊娠期糖尿病患者胰岛细胞功能及糖脂代谢的影响

有氧运动联合抗阻运动对妊娠期糖尿病患者胰岛细胞功能及糖脂代谢的影响

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目的:探究有氧运动联合抗阻运动对妊娠期糖尿病患者胰岛细胞功能及糖脂代谢的影响.方法:将 2021 年 5 月—2023 年 6 月松滋市人民医院的 100 例妊娠期糖尿病患者依据随机数字表法分为对照组 50 例和观察组 50 例.对照组进行常规妊娠期糖尿病干预,观察组则在对照组的基础上加用有氧运动联合抗阻运动.比较两组的干预总有效率、干预前后的胰岛细胞功能[稳态模型评估胰岛素抵抗指数(HOMA-IR)及稳态模型评估β细胞功能指数(HOMA-β)]、糖代谢指标[空腹血糖(FPG)、餐后 2 h血糖(2 h PG)及糖化血红蛋白(HbA1c)]及脂代谢指标[总胆固醇(TC)、三酰甘油(TG)及低密度脂蛋白胆固醇(LDL-C)].结果:观察组的干预总有效率高于对照组(P<0.05).干预前两组的胰岛细胞功能、糖代谢指标及脂代谢指标比较,差异均无统计学意义(P>0.05),干预 4、8 周后,两组的HOMA-β均高于干预前,且观察组均高于对照组,两组的HOMA-IR、糖代谢指标及脂代谢指标均低于干预前,且观察组均低于对照组(P<0.05).结论:有氧运动联合抗阻运动在妊娠期糖尿病患者中的应用效果较好,且可显著改善患者的胰岛细胞功能及糖脂代谢状态.
Influence of Aerobic Exercise Combined with Resistance Exercise for Islet Cell Function,Glucose and Lipid Metabolism of Patients with Gestational Diabetes Mellitus
Objective:To investigate the influence of aerobic exercise combined with resistance exercise for islet cell function,glucose and lipid metabolism of patients with gestational diabetes mellitus.Method:A total of 100 patients with gestational diabetes mellitus in Songzi People's Hospital from May 2021 to June 2023 were divided into control group 50 cases and observation group 50 cases by the random number table method.The control group was treated with routine intervention for gestational diabetes mellitus,the observation group was treated with aerobic exercise combined with resistance exercise on the intervention of control group.The total effective rates,islet cell function[homeostasis model assessment for insulinresistance(HOMA-IR)and homeostasis model assessment β cell function(HOMA-β)],glucose metabolism indexes[fasting plasma glucose(FPG),2 hour postprandial plasma glucose(2 h PG)and glycosylated hemoglobin(HbA1c)]and lipid metabolism indexes[total cholesterol(TC),triacylglycerol(TG)and low density lipoprotein-cholesterol(LDL-C)]before and after the intervention of two groups were compared.Result:The total effective rate of observation group was higher than that of control group(P<0.05).The islet cell function,glucose and lipid metabolism indexes of two groups before the intervention were compared,the differences were not statistically significant(P>0.05).After 4 and 8 weeks of intervention,HOMA-β in both groups were higher those before intervention,and observation group were higher than those of control group,HOMA-IR,glucose metabolism index and lipid metabolism index in both groups were lower than those before intervention,and observation group were lower than those of control group(P<0.05).Conclusion:The application effect of aerobic exercise combined with resistance exercise in patients with gestational diabetes mellitus is better,and it can significantly improve the islet cell function,glucose and lipid metabolism of patients.

Aerobic exerciseResistance exerciseGestational diabetes mellitusIslet cell functionGlucose metabolismLipid metabolism

胡廷雪、胡筱、王勇、华君、胡海钦

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松滋市人民医院药学部 湖北 松滋 434200

有氧运动 抗阻运动 妊娠期糖尿病 胰岛细胞功能 糖代谢 脂代谢

2024

中国医学创新
中国保健协会

中国医学创新

影响因子:1.706
ISSN:1674-4985
年,卷(期):2024.21(8)
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