Clinical Study on the Improvement of Immune Function in Patients with Advanced Cervical Cancer Undergoing Chemotherapy by Press Needle Therapy Combined with Shenmai Injection
Objective:To study the effect of press needle therapy combined with Shenmai Injection on improving immune function in patients with advanced cervical cancer undergoing chemotherapy.Method:A total of 60 patients with advanced cervical cancer who received treatment in Jiujiang NO.1 People's Hospital from August 2018 to January 2022 were selected as clinical research objects,and they were divided into control group and experimental group,with 30 cases in each group.The control group was treated with Shenmai Injection,and the experimental group was treated with press needle therapy on the basis of the control group.T lymphocyte subpopulation situation,Karnofsky(KPS)score,tumor markers,adverse reactions and therapeutic effect were observed in the two groups.Result:After treatment,CD4+ and CD4+/CD8+ in the experimental group were higher than those in the control group,while CD8+ was lower than that in the control group,the differences were statistically significant(P<0.05).There was no significant difference in KPS score before treatment(P>0.05).After treatment,the KPS score of experimental group was significantly higher than that of control group,the difference was statistically significant(P<0.05).There were no significant differences in carbohydrate antigen 125(CA125),carcinoembryonic antigen(CEA),carbohydrate antigen 19-9(CA19-9)between two groups before treatment(P>0.05).After treatment,the tumor markers of the experimental group were lower than those of the control group,the differences were statistically significant(P<0.05).The total incidence of adverse reactions in experimental group(10.00%)was lower than that in control group(33.33%),the difference was statistically significant(P<0.05).The total effective rate of experimental group(96.67%)was higher than that of control group(76.67%),the difference was statistically significant(P<0.05).Conclusion:The combination of press needle therapy and Shenmai Injection in the treatment of patients with advanced cervical cancer undergoing chemotherapy is beneficial to reduce the incidence of adverse reactions,improve the therapeutic effect,strengthen the immune function of patients,and improve the levels of tumor markers.
Press needle therapyShenmai InjectionAdvanced cervical cancerImmune function
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