首页|侧方入路及中间入路腹腔镜手术治疗结直肠癌的围手术期指标比较

侧方入路及中间入路腹腔镜手术治疗结直肠癌的围手术期指标比较

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目的:观察侧方入路及中间入路腹腔镜手术治疗结直肠癌的围手术期指标的差异.方法:选取 2018 年 12 月—2022 年 12 月无锡市惠山区第三人民医院收治的 122 例结直肠癌患者,采用随机数字表法将其分为观察组和对照组,各 61 例.两组均行腹腔镜结直肠癌根治术,观察组选择中间入路,对照组选择侧方入路.比较两组手术时间、术中出血量、淋巴结清扫个数、肛门排气时间、肠鸣音恢复时间、进食时间;比较两组手术前后血清糖类抗原 19-9(CA19-9)、糖类抗原 242(CA242)、癌胚抗原(CEA)水平;比较两组术后并发症发生率.结果:与对照组相比,观察组手术时间、肛门排气时间、肠鸣音恢复时间、进食时间均较短,术中出血量较少,淋巴结清扫个数较多,差异均有统计学意义(P<0.05);手术后两组血清CA19-9、CA242、CEA水平均较手术前降低,差异均有统计学意义(P<0.05),但手术后两组血清CA19-9、CA242、CEA水平比较,差异均无统计学意义(P>0.05);观察组术后并发症发生率为 8.20%(5/61),包括切口感染 3 例、肠梗阻 1 例、吻合口出血 1 例,对照组术后并发症发生率为 9.84%(6/61),包括切口感染 2 例、尿路感染 1 例、肠梗阻 2 例、吻合口瘘 1 例,两组术后并发症发生率比较差异无统计学意义(P>0.05).结论:腹腔镜结直肠癌根治术选择侧方入路或中间入路治疗结直肠癌患者在控制血清肿瘤标志物水平方面效果相当,而中间入路有利于缩短手术时间、降低术中出血量,促进患者术后恢复.
Comparison of Perioperative Indexes between Lateral Approach and Intermediate Approach Laparoscopic Surgery for Colorectal Cancer
Objective:To observe the difference of perioperative indexes between lateral approach and intermediate approach laparoscopic surgery for colorectal cancer.Method:A total of 122 patients with colorectal cancer admitted to Wuxi Huishan District Third People's Hospital from December 2018 to December 2022 were selected and divided into observation group and control group by random number table method,with 61 cases in each group.Laparoscopic radical resection of colorectal cancer was performed in both groups.Intermediate approach was selected in the observation group and lateral approach was selected in the control group.Operation time,intraoperative blood loss,number of lymph node dissection,anal exhaust time,bowel sound recovery time and eating time were compared between the two groups.The serum levels of carbohydrate antigen 19-9(CA19-9),carbohydrate antigen 242(CA242)and carcinoembryonic antigen(CEA)were compared between the two groups before and after operation.The incidence of postoperative complications was compared between the two groups.Result:Compared with the control group,the surgical time,anal exhaust time,bowel sound recovery time,eating time were lower,intraoperative blood loss was less,and lymph node dissection was more in the observation group,the differences were statistically significant(P<0.05).After surgery,the levels of serum CA19-9,CA242 and CEA in the two groups were lower than those before operation,with statistical significance(P<0.05),but there were no statistical significances in the levels of serum CA19-9,CA242 and CEA between the two groups after surgery(P>0.05).The incidence of postoperative complications in the observation group was 8.20%(5/61),including 3 cases of incision infection,1 case of intestinal obstruction,and 1 case of anastomotic bleeding.The incidence of postoperative complications in the control group was 9.84%(6/61),including 2 cases of incision infection,1 case of urinary tract infection,2 cases of intestinal obstruction,and 1 case of anastomotic fistula,there was no statistically significant difference in the incidence of postoperative complications between the two groups(P>0.05).Conclusion:In the treatment of patients with colorectal cancer,lateral approach or intermediate approach is equally effective in controlling the level of serum tumor markers,while the intermediate approach is beneficial to shorten the operation time,reduce the intraoperative blood loss,and promote postoperative recovery.

Colorectal cancerLaparoscopic surgerySurgical approachPerioperative period

孙鋆泽、谢亮海、尹志斌

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无锡市惠山区第三人民医院普外科 江苏 无锡 214183

结直肠癌 腹腔镜手术 手术入路 围手术期

2024

中国医学创新
中国保健协会

中国医学创新

影响因子:1.706
ISSN:1674-4985
年,卷(期):2024.21(9)
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