首页|小儿肺炎支原体肺炎并发消化道系统损害的相关影响因素分析

小儿肺炎支原体肺炎并发消化道系统损害的相关影响因素分析

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目的:探讨小儿肺炎支原体肺炎并发消化道系统损害的相关影响因素.方法:回顾性分析2020年1月—2023年3月南通大学附属南通妇幼保健院收治的132例小儿肺炎支原体肺炎患儿临床资料,根据是否并发消化道系统损害分为消化道系统损害组(n=35)、非消化道系统损害组(n=97).收集患儿一般资料,包括性别、年龄、体重、发热病程、病程、大环内酯类药物开始使用时间、糖皮质激素开始使用时间、红细胞沉降率(ESR)、C反应蛋白(CRP)水平、白细胞(WBC)水平、中性粒细胞百分比.对一般资料进行单因素分析,再对有统计学差异因素的进行多因素logistic回归分析.结果:132例小儿肺炎支原体感染患儿发生 35 例消化道系统损害,发生率 26.52%(35/132).单因素分析显示,两组性别、体重、病程、糖皮质激素开始使用时间、ESR、WBC、中性粒细胞百分比对比,差异均无统计学意义(P>0.05).两组年龄、发热病程、大环内酯类药物开始使用时间、CRP水平比较,差异均有统计学意义(P<0.05).logistic回归分析显示,年龄≤3 岁、发热病程≥7 d、大环内酯类药物使用时间<3 d、CRP≥10 mg/L是小儿肺炎支原体感染并发消化道系统损害的独立危险因素(OR>1 且P<0.05).结论:小儿肺炎支原体肺炎患儿并发消化道系统损害与年龄≤3岁、发热病程≥7 d、大环内酯类药物使用时间<3 d、CRP≥10 mg/L有关.
Analysis of Related Influencing Factors of Digestive Tract System Damage in Mycoplasma Pneumoniae Pneumonia in Children
Objective:To investigate the related influencing factors of digestive tract system damage in mycoplasma pneumoniae pneumonia in children.Method:Clinical data of 132 children with mycoplasma pneumoniae pneumonia admitted to Affiliated Maternity and Child Health Care Hospital of Nantong University from January 2020 to March 2023 were retrospectively analyzed,and they were divided into digestive system damage group(n=35)and non digestive system damage group(n=97)according to whether complicated with digestive tract system damage.General data of the children were collected,including sex,age,weight,fever course,disease course,time when macrocyclic lactones began to be used,time when glucocorticoid began to be used,erythrocyte sedimentation rate(ESR),C reactive protein(CRP)level,white blood cell(WBC)level,and the percentage of neutrophil.Univariate analysis was carried out for the general data,and multivariate logistic regression analysis was carried out for the factors with statistical difference.Result:Among 132 children with mycoplasma pneumoniae infection,35 cases of digestive tract damage,the incidence rate was 26.52%(35/132).Univariate analysis showed that gender,body weight,disease course,glucocorticoid initiation time,ESR,WBC,percentage of neutrophils were compared between the two groups,the differences were not statistically significant(P>0.05).There were statistically significant differences in age,course of fever,start time of macrocyclic lactones and CRP level between the two groups(P<0.05).logistic regression analysis showed that age≤3 years old,duration of fever≥7 d,time of macrocyclic lactones drug use≥3 d,CRP≥10 mg/L were independent risk factors for mycoplasma pneumoniae infection complicated with digestive tract damage in children(OR>1 and P<0.05).Conclusion:Digestive tract system damage in children with mycoplasma pneumoniae pneumonia is associated with age≤3 years old,duration of fever≥7 d,duration of macrocyclic lactones drug use≥5 d,CRP≥10 mg/L.

Mycoplasma pneumoniae pneumonia in childrenDigestive tract system damageInfluencing factorsInflammation levelsMacrocyclic lactones

钱元原、季卫刚、陈艳艳、张娟

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南通大学附属南通妇幼保健院儿科 江苏 南通 226000

小儿肺炎支原体肺炎 消化道系统损害 影响因素 炎症水平 大环内酯类

南通市市级科技计划(2020)

JCZ20018

2024

中国医学创新
中国保健协会

中国医学创新

影响因子:1.706
ISSN:1674-4985
年,卷(期):2024.21(9)
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