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腹腔镜结直肠癌根治术的应用价值

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目的:探讨腹腔镜结直肠癌根治术的应用价值.方法:选取景德镇市第二人民医院 2021 年3 月—2023 年 2 月收治的 68 例结直肠癌患者为对象,按照自然数顺序采用抽签方式将患者随机分为两组,其中对照组(n=34)采用常规开腹手术治疗,观察组(n=34)采用腹腔镜结直肠癌根治术治疗.对比两组临床恢复指标、炎症因子指标、胃肠功能指标、氧化应激反应指标及术后并发症发生率.结果:与对照组比较,观察组术中出血量更少,手术切口更短,且术后各指标恢复更佳,住院时间更短(P<0.05).术后1周,观察组血清炎症因子水平均低于对照组(P<0.05).术后 1 周,两组胃动素及与胃泌素水平均降低,观察组指标均高于对照组(P<0.05).术后 1 周,观察组丙二醛(MDA)水平低于对照组,血清超氧化物歧化酶(SOD)水平高于对照组(P<0.05).观察组并发症发生率低于对照组(P<0.05).结论:腹腔镜结直肠癌根治术满足患者微创治疗需求,对胃肠功能的影响小,可减轻炎症因子,缓解氧化应激反应,术后并发症少,帮助患者更快恢复.
Application Value of Laparoscopic Radical Resection of Colorectal Cancer
Objective:To investigate the application value of laparoscopic radical resection of colorectal cancer.Method:A total of 68 patients with colorectal cancer admitted to Jingdezhen Second People's Hospital from March 2021 to February 2023 were selected,they were randomly divided into two groups by drawing lots according to natural number order,the control group(n=34)was treated by conventional open surgery,and the observation group(n=34)was treated by laparoscopic radical resection of colorectal cancer.The indicators of clinical recovery,inflammatory factors indicators,gastrointestinal function indicators,oxidative stress reaction indicators and postoperative complication rates of the two groups were compared.Result:Compared with the control group,intraoperative blood loss was less in the observation group,surgical incision was shorter,the postoperative recovery of all indexes was better,and the hospital stay was shorter(P<0.05).1 week after operation,the levels of motilin and gastrin in both groups were decreased,and the indexes in the observation group were higher than those in the control group(P<0.05).1 week after operation,the levels of motilin and gastrin in two groups were significantly decreased,and the indicators in the observation group were higher than those in the control group(P<0.05).1 week after surgery,malondialdehyde(MDA)level was lower than that in the control group,and the superoxide dismutase(SOD)level was higher than that in the control group(P<0.05).The incidence of complication of observation group was lower than that of control group(P<0.05).Conclusion:Laparoscopic radical resection of colorectal cancer meets the needs of patients for minimally invasive treatment,has little impact on gastrointestinal function,can reduce inflammatory factors,relieve oxidative stress reaction,reduce postoperative complications,and help patients recover faster.

Laparoscopic radical resection of colorectal cancerOpen surgeryInflammatory factorsGastrointestinal functionComplication

韩宏景、蔡雪芳、宋伟林

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景德镇市第二人民医院普外二科 江西 景德镇 333000

景德镇市第二人民医院血透室 江西 景德镇 333000

腹腔镜结直肠癌根治术 开腹手术 炎症因子 胃肠功能 并发症

景德镇市科技计划

20221SFZC033

2024

中国医学创新
中国保健协会

中国医学创新

影响因子:1.706
ISSN:1674-4985
年,卷(期):2024.21(10)
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