Value of DCE-MRI Quantitative Parameters in Differential Diagnosis of Benign and Malignant Lung Tumors
Objective:To explore the value of quantitative parameters of Dynamic Enhanced Magnetic Resonance Imaging(DCE-MRI)for differential diagnosis of benign and malignant lung tumors.Method:A total of 100 patients with lung tumor were selected from 73rd Group Military Hospital of the Chinese People's Liberation Army from February 2022 to April 2023,all patients received routine magnetic resonance imaging(MRI)plain scan,DCE-MRI scan and pathological examination after admission.The DCE-MRI quantitative permeability parameters[blood reflux constant(Kep),volume transfer constant(Ktrans),plasma volume fraction(Vp),extracellular space volume fraction(Ve)]of benign and malignant lung tumors were compared,the value of DCE-MRI quantitative parameters for the differential diagnosis of benign and malignant lung tumors were analyzed.Result:Among 100 patients with lung tumour,41 benign tumour and 59 malignant tumour were diagnosed by pathological examination.The Ktrans and Kep of the malignant tumour group were higher than those of the benign tumour group(P<0.05).There were no significant differences in Ve and Vp between malignant tumor group and benign tumor group(P>0.05).Receiver operating characteristic(ROC)curve was drawn,and the results showed that the area under the curve(AUC)of Ktrans and Kep alone and combined in the diagnosis of benign and malignant lung tumors were 0.835,0.872 and 0.945,all of which had certain diagnostic value.When Ktrans and Kep were 0.525 min-1 and 0.920 min-1,respectively,the best diagnostic efficiency can be obtained,and the combined diagnosis value of the two was higher.Conclusion:DCE-MRI quantitative parameters have high value in differential diagnosis of benign and malignant lung tumors.Ktrans and Kep values can be used to determine benign and malignant lung tumors.
Lung tumorBenign and malignantDynamic enhanced magnetic resonance imagingTransport constantBlood reflux constant
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