DCE-MRI定量参数鉴别诊断肺部肿瘤良恶性的价值
Value of DCE-MRI Quantitative Parameters in Differential Diagnosis of Benign and Malignant Lung Tumors
林丹桂 1刘昌华1
作者信息
- 1. 中国人民解放军陆军第七十三集团军医院医学影像科 福建 厦门 361003
- 折叠
摘要
目的:探究动态增强磁共振成像(DCE-MRI)定量参数鉴别诊断肺部肿瘤良恶性的价值.方法:选取中国人民解放军陆军第七十三集团军医院 2022 年 2 月—2023 年 4 月收治的 100 例肺部肿瘤患者,所有患者入院后均接受常规磁共振成像(MRI)平扫、DCE-MRI扫描及病理检查.比较良恶性肺部肿瘤DCE-MRI定量渗透性参数[血液回流常数(Kep)、容积转运常数(Ktrans)、血浆容积分数(Vp)、血管外细胞外间隙容积分数(Ve)],分析DCE-MRI定量参数鉴别诊断肺部肿瘤良恶性的价值.结果:100例肺部肿瘤患者中,经病理检查确诊为 41 例良性肿瘤,59 例恶性肿瘤.恶性肿瘤组的Ktrans、Kep均比良性肿瘤组高(P<0.05).两组Ve、Vp比较,差异均无统计学意义(P>0.05).绘制受试者操作特征(ROC)曲线,结果显示,Ktrans、Kep单独及联合诊断肺部肿瘤良恶性的曲线下面积(AUC)为 0.835、0.872、0.945,均有一定诊断价值.当Ktrans、Kep分别为 0.525 min-1、0.920 min-1 时,可获得最佳诊断效能,且二者联合诊断的价值较高.结论:DCE-MRI定量参数鉴别诊断肺部肿瘤良恶性的价值较高,可通过检测其Ktrans、Kep值来判断肺部肿瘤的良恶性.
Abstract
Objective:To explore the value of quantitative parameters of Dynamic Enhanced Magnetic Resonance Imaging(DCE-MRI)for differential diagnosis of benign and malignant lung tumors.Method:A total of 100 patients with lung tumor were selected from 73rd Group Military Hospital of the Chinese People's Liberation Army from February 2022 to April 2023,all patients received routine magnetic resonance imaging(MRI)plain scan,DCE-MRI scan and pathological examination after admission.The DCE-MRI quantitative permeability parameters[blood reflux constant(Kep),volume transfer constant(Ktrans),plasma volume fraction(Vp),extracellular space volume fraction(Ve)]of benign and malignant lung tumors were compared,the value of DCE-MRI quantitative parameters for the differential diagnosis of benign and malignant lung tumors were analyzed.Result:Among 100 patients with lung tumour,41 benign tumour and 59 malignant tumour were diagnosed by pathological examination.The Ktrans and Kep of the malignant tumour group were higher than those of the benign tumour group(P<0.05).There were no significant differences in Ve and Vp between malignant tumor group and benign tumor group(P>0.05).Receiver operating characteristic(ROC)curve was drawn,and the results showed that the area under the curve(AUC)of Ktrans and Kep alone and combined in the diagnosis of benign and malignant lung tumors were 0.835,0.872 and 0.945,all of which had certain diagnostic value.When Ktrans and Kep were 0.525 min-1 and 0.920 min-1,respectively,the best diagnostic efficiency can be obtained,and the combined diagnosis value of the two was higher.Conclusion:DCE-MRI quantitative parameters have high value in differential diagnosis of benign and malignant lung tumors.Ktrans and Kep values can be used to determine benign and malignant lung tumors.
关键词
肺部肿瘤/良恶性/动态增强磁共振成像/容积转运常数/血液回流常数Key words
Lung tumor/Benign and malignant/Dynamic enhanced magnetic resonance imaging/Transport constant/Blood reflux constant引用本文复制引用
出版年
2024
国家科技期刊平台
NSTL
万方数据