首页|超声心动图结合血清超敏C反应蛋白预测高血压性心脏病预后的临床价值

超声心动图结合血清超敏C反应蛋白预测高血压性心脏病预后的临床价值

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目的:分析超声心动图结合血清超敏C反应蛋白(hs-CRP)水平预测高血压性心脏病预后的临床价值.方法:回顾性分析 2020 年 2 月—2022 年 2 月于山东省泰山医院就诊的 80 例高血压性心脏病患者,同时招募 70 例于山东省泰山医院体检健康人士,分别记为观察组与参照组.比较两组超声心动图左室流出道速度-时间积分(LVOT-VTI)、左室舒张末期直径(LVEDD)、左室收缩末期直径(LVESD)、hs-CRP水平.对观察组患者随访 1 年,根据是否出现心血管不良事件分为预后不良组和预后良好组,观察入院时超声心动图、hs-CRP对高血压性心脏病患者预后的预测价值.结果:观察组超声心动图LVOT-VTI、LVEDD、LVESD及hs-CRP水平均高于参照组(P<0.05),观察组预后良好占比 80.00%,预后不良占比 20.00%,预后不良组LVOT-VTI、LVEDD、LVESD、hs-CRP水平均高于预后良好组(P<0.05),LVOT-VTI、LVEDD、LVESD、hs-CRP均为高血压性心脏病预后不良的影响因素(P<0.05),LVOT-VTI、LVEDD、LVESD、hs-CRP及四者联合预测高血压性心脏病患者预后不良的AUC值分别为 0.791、0.802、0.821、0.813、0.892(P<0.05),且四者联合的AUC值均高于单独指标预测的AUC值(P<0.05).结论:高血压性心脏病患者超声心动图参数LVOT-VTI、LVEDD、LVESD、hs-CRP水平异常,预后不良患者超声心动图参数、hs-CRP水平高于预后良好患者,超声心动图参数联合hs-CRP水平对高血压性心脏病患者预后具有一定预测价值.
Clinical Value of Echocardiography Combined with Serum Hypersensitive C Reactive Protein in Predicting Prognosis of Hypertensive Heart Disease
Objective:To analyze the clinical value of echocardiography combined with serum hypersensitive C reactive protein(hs-CRP)level in predicting the prognosis of hypertensive heart disease.Method:A total of 80 patients with hypertensive heart disease who received medical treatment in Shandong Provincial Taishan Hospital from February 2020 to February 2022 were retrospectively analyzed,and 70 healthy people who underwent physical examination in Shandong Province Taishan Hospital were recruited and recorded as observation group and reference group,respectively.Left ventricular outflow velocity-time integral(LVOT-VTI),left ventricular end-diastolic diameter(LVEDD),left ventricular end-systolic diameter(LVESD)and hs-CRP levels were compared between the two groups.The observation group was followed up for 1 year and divided into poor prognosis group and good prognosis group according to the occurrence of adverse cardiovascular events.The prognostic value of echocardiography and hs-CRP on admission to hypertensive heart disease patients was observed.Result:The echocardiography levels of LVOT-VTI,LVEDD,LVESD and hs-CRP in the observation group were higher than those in the reference group(P<0.05).In the observation group,good prognosis accounted for 80.00%and poor prognosis accounted for 20.00%.The levels of LVOT-VTI,LVEDD,LVESD and hs-CRP in the poor prognosis group were higher than those in the good prognosis group(P<0.05),and LVOT-VTI,LVEDD,LVESD and hs-CRP were all influential factors for the poor prognosis of hypertensive heart disease(P<0.05).The AUC values of LVOT-VTI,LVEDD,LVESD,hs-CRP and the combined prediction of poor prognosis in hypertensive heart disease patients were 0.791,0.802,0.821,0.813,0.892,respectively(P<0.05).The combined AUC values of the four indexes were higher than those predicted by the single index(P<0.05).Conclusion:The levels of echocardiographic parameters LVOT-VTI,LVEDD,LVESD and hs-CRP in patients with hypertensive heart disease are abnormal,and the levels of echocardiography and hs-CRP in patients with poor prognosis are higher than those in patients with good prognosis.The combined echocardiographic parameters and hs-CRP have certain prognostic value in patients with hypertensive heart disease.

EchocardiographyHypersensitive C reactive proteinHypertensive heart diseaseSensitivitySpecificity

程龙、王冉冉、李慧、程春梅

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山东省泰山医院心内科 山东 泰安 271099

莱芜职业技术学院妇幼教研室 山东 莱芜 271199

莱芜职业技术学院护理教研室 山东 莱芜 271199

聊城鲁西骨科医院检验科 山东 聊城 252000

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超声心动图 超敏C反应蛋白 高血压性心脏病 敏感度 特异度

2024

中国医学创新
中国保健协会

中国医学创新

影响因子:1.706
ISSN:1674-4985
年,卷(期):2024.21(10)
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