首页|坦索罗辛联合复方黄柏制剂坐浴治疗ⅢB型前列腺炎(湿热蕴结夹瘀证)的临床研究

坦索罗辛联合复方黄柏制剂坐浴治疗ⅢB型前列腺炎(湿热蕴结夹瘀证)的临床研究

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目的:探究坦索罗辛联合复方黄柏制剂坐浴在ⅢB型前列腺炎(湿热蕴结夹瘀证)患者中的应用效果.方法:将 2022 年 7 月—2023 年 5 月福建中医药大学附属第三人民医院收治的 80 例ⅢB型前列腺炎(湿热蕴结夹瘀证)患者根据随机数字表法分为对照组(n=40)和观察组(n=40).对照组进行坦索罗辛联合温水坐浴治疗,观察组则进行坦索罗辛联合复方黄柏制剂坐浴治疗.比较两组总有效率、不良反应发生率、3 个月内复发率,以及治疗前后美国国立卫生研究院慢性前列腺炎症状指数(NIH-CPSI)、中医症候积分及前列腺液卵磷脂小体计数.结果:观察组总有效率显著高于对照组,3 个月内复发率显著低于对照组(P<0.05);两组各不良反应发生率比较,差异均无统计学意义(P>0.05);治疗 1、2 个疗程后,观察组NIH-CPSI评分及中医症候积分均显著低于对照组,前列腺液卵磷脂小体计数显著高于对照组(P<0.05).结论:坦索罗辛联合复方黄柏制剂坐浴在ⅢB型前列腺炎(湿热蕴结夹瘀证)患者中的治疗效果较好,可有效改善患者的症状体征,控制复发率.
Clinical Study on Tamsulosin Combined with Sitz Bath with Compound Huangbai Preparation in the Treatment of Type ⅢB Prostatitis(Syndrome of Dampness-heat Amassment Pattern Complicated Stasis)
Objective:To explore the application effect of Tamsulosin combined with sitz bath with Compound Huangbai Preparation in the treatment of type ⅢB prostatitis(syndrome of dampness-heat amassment pattern complicated stasis).Method:A total of 80 patients with type ⅢB prostatitis(syndrome of dampness-heat amassment pattern complicated stasis)admitted to the Third People's Hospital Affiliated to Fujian University of Traditional Chinese Medicine from July 2022 to May 2023 were divided into control group(n=40)and observation group(n=40)according to random number table method.The control group was treated with Tamsulosin combined with warm water sitz bath and the observation group was treated with Tamsulosin combined with sitz bath with Compound Huangbai Preparation.The total effective rate,incidence of adverse reactions,recurrence rate within 3 months,national institutes of health chronic prostatitis syndrome index(NIH-CPSI)before and after treatment,TCM symptom integrations and the count of lecithin corpuscle in expressed prostatic secretion were compared between the two groups.Result:The total effective rate of observation group was significantly higher than that of control group,and the recurrence rate within 3 months was significantly lower than that of control group(P<0.05).There were no significant differences in the incidences of adverse reactions between the two groups(P>0.05).After 1 and 2 courses of treatment,NIH-CPSI scores and TCM syndrome integrations in observation group were significantly lower than those in control group,and the count of lecithin corpuscle in expressed prostatic secretion was significantly higher than that in control group(P<0.05).Conclusion:Tamsulosin combined with sitz bath with Compound Huangbai Preparation in patients with type ⅢB prostatitis(syndrome of dampness-heat amassment pattern complicated stasis)has a good therapeutic effect,which can effectively improve the symptoms and signs of patients and control the recurrence rate.

TamsulosinCompound Huangbai PreparationSitz bathType ⅢB prostatitisSyndrome of dampness-heat amassment pattern complicated stasis

叶华、曹超、甘晶、冯杰、魏书章

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福建中医药大学附属第三人民医院泌尿外科 福建 闽侯 350108

坦索罗辛 复方黄柏制剂 坐浴 ⅢB型前列腺炎 湿热蕴结夹瘀证

福建中医药大学校管科研项目

XB2022039

2024

中国医学创新
中国保健协会

中国医学创新

影响因子:1.706
ISSN:1674-4985
年,卷(期):2024.21(12)
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