首页|重复经颅磁刺激外周-中枢闭环治疗模式治疗脊髓损伤后神经源性膀胱的研究

重复经颅磁刺激外周-中枢闭环治疗模式治疗脊髓损伤后神经源性膀胱的研究

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目的:研究重复经颅磁刺激外周-中枢闭环治疗模式对脊髓损伤后神经源性膀胱治疗的影响.方法:选取 2020 年 5 月—2022 年 2 月茂名市人民医院收治的脊髓损伤后神经源性膀胱患者 80 例作为研究对象,采用随机数字表法将患者分为A组、B组,各 40 例,均进行常规康复治疗,A组加用低频电刺激治疗,B组加用重复经颅磁刺激外周-中枢闭环治疗模式.对比两组治疗前后尿流动力学、膀胱容量与压力、生活质量.结果:治疗 4 周后,两组残余尿量较治疗前均降低,最大尿流率、最大膀胱容量均较治疗前升高,膀胱内压力较治疗前均降低,且B组均优于A组(P<0.05);两组每天单次排尿量较治疗前均提高,排尿次数均较治疗前降低,且B组均优于A组(P<0.05);两组泌尿症状困扰评分量表(USDS)、国际下尿路症状(LUTS)评分均较治疗前降低,且B组均较A组低(P<0.05).治疗 4 周后,两组世界卫生组织生存质量测定简表(WHOQOL-BREF)中生理、心理、社会关系、生活环境评分均较治疗前提高,且B组均较A组高,差异均有统计学意义(P<0.05).结论:重复经颅磁刺激外周-中枢闭环治疗模式对脊髓损伤后神经源性膀胱治疗后的尿流动力学具有改善作用,且可以增加膀胱容量,改善排尿尿量及次数,改善生活质量.
Study on the Treatment of Neurogenic Bladder after Spinal Cord Injury Using Repetitive Transcranial Magnetic Stimulation Peripheral Central Closed-loop Therapy Mode
Objective:To investigate the effect of repeated transcranial magnetic stimulation peripheral central closed-loop therapy mode on neurogenic bladder therapy after spinal cord injury.Method:A total of 80 patients with neurogenic bladder after spinal cord injury admitted to Maoming People's Hospital from May 2020 to February 2022 were selected as the study objects,and they were divided into group A and group B by random number table method,with 40 cases in each group,they received conventional rehabilitation treatment,group A received low-frequency electrical stimulation treatment,group B received repeated transcranial magnetic stimulation peripheral and central closed-loop treatment mode.Urinary flow dynamics,bladder volume and pressure and quality of life were compared between the two groups before and after treatment.Result:After 4 weeks of treatment,the residual urine volume in both groups were lower than those before treatment,and the maximum urine flow rate and maximum bladder volume were higher than those before treatment,and the bladder pressure were lower than those before treatment,and those in group B were better than those in group A(P<0.05);the daily urine volume in both group were higher than those before treatment,and the frequency of urination were lower than those before treatment,and those in group B were better than those in group A(P<0.05);the urinary symptom distress scale(USDS)and international lower urinary tract syndrome(LUTS)scores in both groups were lower than those before treatment,and those in group B were lower than those in group A(P<0.05).After 4 weeks of treatment,the scores of physiology,psychology,social relationship and living environment in the world health organization quality of life(WHOQOL)-BREF in both groups were improved compared with those before treatment,and those in group B were higher than those in group A,the differences were statistically significant(P<0.05).Conclusion:Repeated transcranial magnetic stimulation of peripheral central closed-loop therapy mode can improve the urinary flow dynamics after neurogenic bladder therapy after spinal cord injury,and can increase the bladder capacity,improve the volume and frequency of urination,and improve the quality of life.

Spinal cord injuryNeurogenic bladderRepeat magnetic stimulationPeripheral central closed-loop therapy modeUrodynamics

李文、梁寿一、周嘉铭、陈锦媚

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茂名市人民医院康复医学科 广东 茂名 525000

脊髓损伤 神经源性膀胱 重复经颅磁刺激 外周-中枢闭环治疗模式 尿流动力学

茂名市科技计划

200415084556175

2024

中国医学创新
中国保健协会

中国医学创新

影响因子:1.706
ISSN:1674-4985
年,卷(期):2024.21(12)
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