The Application of Thoracic Paravertebral Nerve Block Combined with General Anesthesia Guided by Ultrasound in Radical Operation of Breast Cancer and Its Effects on Pain and Hemodynamics
Objective:To analyze the effect of ultrasound guided thoracic paravertebral nerve block combined with general anesthesia in breast cancer radical surgery.Method:Using retrospective analysis method,according to the different anesthesia scheme,70 patients from June 2021 to July 2023 in Xingshan Hospital,Zhongnan Hospital of Wuhan University were divided into reference group and study group,35 cases of general anesthesia with ultrasound guided thoracic nerve block into the study group,35 cases of only general anesthesia were included in the reference group.The anesthetic effect,hemodynamic changes at the time of entering the operation room(T0),anesthesia(T1),intubation(T2),skin incision(T3),axillary dissection(T4),extubation(T5)and leaving the room(T6)and pain scores at different time points after operation were compared between the two groups.Result:At T3 and T4,the EEG double-frequency index of the study group were lower than those of the reference group,the differences were significant(P<0.05).At T1,T2,T3,T4,T5 and T6,the heart rate and mean arterial depression in the study group were lower than those in the reference group,the differences were statistically significant(P<0.05);there were no statistically significant differences in heart rate and mean arterial pressure at each time point in the study group(P>0.05).In the reference group,the heart rate and mean arterial pressure at each time point after T0 were higher than that at T0,the differences were statistically significant(P<0.05).The pain scores of the study group at 2,6,8 and 12 h were lower than those of the reference group,the differences were statistically significant(P<0.05).Conclusion:Ultrasound guided thoracic paravertebral nerve block combined with general anesthesia can enhance the anesthesia effect,reduce the fluctuation of perioperative hemodynamic fluctuations,and maintain long-term postoperative analgesia.
Breast cancerRadical mastectomy of breast cancerUltrasoundThoracic paravertebral nerve block combined with general anesthesia
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